Epidemiology of obesity and diabetes and their cardiovascular complications

SN Bhupathiraju, FB Hu - Circulation research, 2016 - Am Heart Assoc
Obesity and diabetes mellitus have reached epidemic proportions in the past few years.
During 2011 to 2012, more than one-third of the US population was obese. Although recent …

Genetics of obesity: what genetic association studies have taught us about the biology of obesity and its complications

MO Goodarzi - The lancet Diabetes & endocrinology, 2018 - thelancet.com
Genome-wide association studies (GWAS) for BMI, waist-to-hip ratio, and other adiposity
traits have identified more than 300 single-nucleotide polymorphisms (SNPs). Although …

Gene-diet interaction and precision nutrition in obesity

Y Heianza, L Qi - International journal of molecular sciences, 2017 - mdpi.com
The rapid rise of obesity during the past decades has coincided with a profound shift of our
living environment, including unhealthy dietary patterns, a sedentary lifestyle, and physical …

Gene–obesogenic environment interactions in the UK Biobank study

J Tyrrell, AR Wood, RM Ames… - International journal …, 2017 - academic.oup.com
Background: Previous studies have suggested that modern obesogenic environments
accentuate the genetic risk of obesity. However, these studies have proven controversial as …

[HTML][HTML] The epigenetic connection between the gut microbiome in obesity and diabetes

M Sharma, Y Li, ML Stoll, TO Tollefsbol - Frontiers in genetics, 2020 - frontiersin.org
Metabolic diseases are becoming an alarming health issue due to elevated incidences of
these diseases over the past few decades. Various environmental factors are associated …

Obesity and eating behavior from the perspective of twin and genetic research

K Silventoinen, H Konttinen - Neuroscience & biobehavioral reviews, 2020 - Elsevier
Obesity has dramatically increased during the last decades and is currently one of the most
serious global health problems. We present a hypothesis that obesity is a neuro-behavioral …

[HTML][HTML] FTO genotype and weight loss in diet and lifestyle interventions: a systematic review and meta-analysis

L Xiang, H Wu, A Pan, B Patel, G Xiang, L Qi… - The American journal of …, 2016 - Elsevier
abstract Background: Studies have suggested that the fat mass and obesity–associated
(FTO) genotype is associated with individual variability in weight loss in response to …

Genetics of cardiovascular disease: How far are we from personalized CVD risk prediction and management?

M Vrablik, D Dlouha, V Todorovova, D Stefler… - International journal of …, 2021 - mdpi.com
Despite the rapid progress in diagnosis and treatment of cardiovascular disease (CVD), this
disease remains a major cause of mortality and morbidity. Recent progress over the last two …

Technologies, strategies, and cautions when deconvoluting genome‐wide association signals: FTO in focus

MC Pahl, SFA Grant, RL Leibel… - Obesity …, 2023 - Wiley Online Library
Genome‐wide association studies have revealed a plethora of genetic variants that
correlate with polygenic conditions. However, causal molecular mechanisms have proven …

Health issues in Hispanic/Latino youth.

CR Isasi, D Rastogi, K Molina - Journal of Latina/o psychology, 2016 - psycnet.apa.org
Este artículo de revisión se centra en la obesidad, el asma y la salud mental, problemas de
salud importantes que afectan a jóvenes hispanos. También se discute la carga de estas …