[HTML][HTML] Neurosteroids as regulators of neuroinflammation

C Yilmaz, K Karali, G Fodelianaki, A Gravanis… - Frontiers in …, 2019 - Elsevier
Neuroinflammation is a physiological protective response in the context of infection and
injury. However, neuroinflammation, especially if chronic, may also drive …

Estrogens as neuroprotectants: estrogenic actions in the context of cognitive aging and brain injury

EB Engler-Chiurazzi, CM Brown, JM Povroznik… - Progress in …, 2017 - Elsevier
There is ample empirical evidence to support the notion that the biological impacts of
estrogen extend beyond the gonads to other bodily systems, including the brain and …

Sex-related responses after traumatic brain injury: Considerations for preclinical modeling

CB Späni, DJ Braun, LJ Van Eldik - Frontiers in neuroendocrinology, 2018 - Elsevier
Traumatic brain injury (TBI) has historically been viewed as a primarily male problem, since
men are more likely to experience a TBI because of more frequent participation in activities …

Treatment of traumatic brain injury with anti-inflammatory drugs

PJ Bergold - Experimental neurology, 2016 - Elsevier
Traumatic brain injury rapidly induces inflammation. This inflammation is produced both by
endogenous brain cells and circulating inflammatory cells that enter from the brain. Together …

The role of inhaled estradiol and myrtenol, alone and in combination, in modulating behavioral and functional outcomes following traumatic experimental brain injury …

MA Rajizadeh, M Khaksari, MA Bejeshk… - Neurocritical Care, 2023 - Springer
Background Traumatic brain injury (TBI) is an important and growing cause of disability
worldwide, and its cognitive consequences may be particularly significant. This study …

Ellagic acid prevents cognitive and hippocampal long-term potentiation deficits and brain inflammation in rat with traumatic brain injury

Y Farbood, A Sarkaki, M Dianat, A Khodadadi… - Life Sciences, 2015 - Elsevier
Aims Traumatic brain injury (TBI) remains one of the main clinical problems globally and is a
common cause of death among youth. Cognitive defects such as thinking, memory and …

Progesterone neuroprotection: the background of clinical trial failure

M Schumacher, C Denier, JP Oudinet, D Adams… - The Journal of steroid …, 2016 - Elsevier
Since the first pioneering studies in the 1990s, a large number of experimental animal
studies have demonstrated the neuroprotective efficacy of progesterone for brain disorders …

Adolescent intermittent ethanol exposure produces Sex-Specific changes in BBB Permeability: A potential role for VEGFA

AS Vore, TM Barney, MM Deak, EI Varlinskaya… - Brain, behavior, and …, 2022 - Elsevier
Binge drinking that typically begins during adolescence can have long-lasting
neurobehavioral consequences, including alterations in the central and peripheral immune …

Neuropharmacology in traumatic brain injury: from preclinical to clinical neuroprotection?

D Lerouet, C Marchand‐Leroux… - Fundamental & clinical …, 2021 - Wiley Online Library
Traumatic brain injury (TBI) constitutes a major health problem worldwide and is a leading
cause of death and disability in individuals, contributing to devastating socioeconomic …

Neural stem cell transplantation promotes functional recovery from traumatic brain injury via brain derived neurotrophic factor-mediated neuroplasticity

LL Xiong, Y Hu, P Zhang, Z Zhang, LH Li, GD Gao… - Molecular …, 2018 - Springer
Traumatic brain injury (TBI) induces cognitive impairments, motor and behavioral deficits.
Previous evidences have suggested that neural stem cell (NSC) transplantation could …