Updated review of advances in microRNAs and complex diseases: taxonomy, trends and challenges of computational models

L Huang, L Zhang, X Chen - Briefings in Bioinformatics, 2022 - academic.oup.com
Since the problem proposed in late 2000s, microRNA–disease association (MDA)
predictions have been implemented based on the data fusion paradigm. Integrating diverse …

[HTML][HTML] Application of machine learning in microbiology

K Qu, F Guo, X Liu, Y Lin, Q Zou - Frontiers in microbiology, 2019 - frontiersin.org
Microorganisms are ubiquitous and closely related to people's daily lives. Since they were
first discovered in the 19th century, researchers have shown great interest in …

Using network distance analysis to predict lncRNA–miRNA interactions

L Zhang, P Yang, H Feng, Q Zhao, H Liu - … sciences: computational life …, 2021 - Springer
LncRNA–miRNA interactions contribute to the regulation of therapeutic targets and
diagnostic biomarkers in multifarious human diseases. However, it remains difficult to …

Identification of miRNA–disease associations via deep forest ensemble learning based on autoencoder

W Liu, H Lin, L Huang, L Peng, T Tang… - Briefings in …, 2022 - academic.oup.com
Increasing evidences show that the occurrence of human complex diseases is closely
related to microRNA (miRNA) variation and imbalance. For this reason, predicting disease …

Neural inductive matrix completion with graph convolutional networks for miRNA-disease association prediction

J Li, S Zhang, T Liu, C Ning, Z Zhang, W Zhou - Bioinformatics, 2020 - academic.oup.com
Motivation Predicting the association between microRNAs (miRNAs) and diseases plays an
import role in identifying human disease-related miRNAs. As identification of miRNA …

[HTML][HTML] Ensemble of decision tree reveals potential miRNA-disease associations

X Chen, CC Zhu, J Yin - PLoS computational biology, 2019 - journals.plos.org
In recent years, increasing associations between microRNAs (miRNAs) and human
diseases have been identified. Based on accumulating biological data, many computational …

Updated review of advances in microRNAs and complex diseases: towards systematic evaluation of computational models

L Huang, L Zhang, X Chen - Briefings in Bioinformatics, 2022 - academic.oup.com
Currently, there exist no generally accepted strategies of evaluating computational models
for microRNA-disease associations (MDAs). Though K-fold cross validations and case …

DAESTB: inferring associations of small molecule–miRNA via a scalable tree boosting model based on deep autoencoder

L Peng, Y Tu, L Huang, Y Li, X Fu… - Briefings in …, 2022 - academic.oup.com
MicroRNAs (miRNAs) are closely related to a variety of human diseases, not only regulating
gene expression, but also having an important role in human life activities and being viable …

Updated review of advances in microRNAs and complex diseases: experimental results, databases, webservers and data fusion

L Huang, L Zhang, X Chen - Briefings in Bioinformatics, 2022 - academic.oup.com
MicroRNAs (miRNAs) are gene regulators involved in the pathogenesis of complex
diseases such as cancers, and thus serve as potential diagnostic markers and therapeutic …

RNMFLP: predicting circRNA–disease associations based on robust nonnegative matrix factorization and label propagation

L Peng, C Yang, L Huang, X Chen… - Briefings in …, 2022 - academic.oup.com
Circular RNAs (circRNAs) are a class of structurally stable endogenous noncoding RNA
molecules. Increasing studies indicate that circRNAs play vital roles in human diseases …