Irritable bowel syndrome (IBS) is a functional disorder which affects a large proportion of the
population globally. The precise etiology of IBS is still unknown, although consensus …

The enteric nervous system (ENS) is the largest division of the peripheral nervous system
and closely resembles components and functions of the central nervous system. Although …

Genetic factors are recognized to contribute to peptic ulcer disease (PUD) and other
gastrointestinal diseases, such as gastro-oesophageal reflux disease (GORD), irritable …

Functional bowel disorders are highly prevalent disorders found worldwide. These disorders
have the potential to affect all members of society, regardless of age, sex, race, creed, color …

Managing irritable bowel syndrome (IBS) has attracted international attention because
single-agent therapy rarely relieves bothersome symptoms for all patients. The Japanese …

Traditionally, irritable bowel syndrome has been considered to be a disorder with no known
underlying structural or biochemical explanation, but this concept is likely to be outdated. In …

Communication between the brain and gut is not one-way, but a bidirectional highway
whereby reciprocal signals between the two organ systems are exchanged to coordinate …

Purpose There is a critical need for population-based prospective cohort studies because
they follow individuals before the onset of disease, allowing for studies that can identify …

Abstract Background and Summary: Traditionally, functional gastrointestinal disorders
(FGID), including functional dyspepsia or irritable bowel syndrome (IBS), are defined by …

Chronic unexplained gastrointestinal symptoms impact more than 1 in 5 Americans and their
families; these disorders include the irritable bowel syndrome (IBS) and functional …