[HTML][HTML] Advanced glycation end products and oxidative stress in type 2 diabetes mellitus

K Nowotny, T Jung, A Höhn, D Weber, T Grune - Biomolecules, 2015 - mdpi.com
Type 2 diabetes mellitus (T2DM) is a very complex and multifactorial metabolic disease
characterized by insulin resistance and β cell failure leading to elevated blood glucose …

Hyperglycemia and glycation in diabetic complications

A Negre-Salvayre, R Salvayre, N Augé… - Antioxidants & redox …, 2009 - liebertpub.com
Diabetes mellitus is a multifactorial disease, classically influenced by genetic determinants
of individual susceptibility and by environmental accelerating factors, such as lifestyle. It is …

[图书][B] Handbook of Food Analysis: Volume 1: Physical Characterization and Nutrient Analysis

LML Nollet - 2004 - taylorfrancis.com
This two-volume handbook supplies food chemists with essential information on the physical
and chemical properties of nutrients, descriptions of analytical techniques, and an …

[HTML][HTML] Understanding the role of protein glycation in the amyloid aggregation process

I Sirangelo, C Iannuzzi - International Journal of Molecular Sciences, 2021 - mdpi.com
Protein function and flexibility is directly related to the native distribution of its structural
elements and any alteration in protein architecture leads to several abnormalities and …

[HTML][HTML] Single-site glycine-specific labeling of proteins

L Purushottam, SR Adusumalli, U Singh… - Nature …, 2019 - nature.com
Labeling of native proteins invites interest from diverse segments of science. However, there
remains the significant unmet challenge in precise labeling at a single site of a protein. Here …

[HTML][HTML] Insulin glycation by methylglyoxal results in native-like aggregation and inhibition of fibril formation

LMA Oliveira, A Lages, RA Gomes, H Neves… - BMC biochemistry, 2011 - Springer
Background Insulin is a hormone that regulates blood glucose homeostasis and is a central
protein in a medical condition termed insulin injection amyloidosis. It is intimately associated …

[HTML][HTML] Mass spectrometric determination of early and advanced glycation in biology

N Rabbani, A Ashour, PJ Thornalley - Glycoconjugate journal, 2016 - Springer
Protein glycation in biological systems occurs predominantly on lysine, arginine and N-
terminal residues of proteins. Major quantitative glycation adducts are found at mean extents …

[HTML][HTML] Antidiabetic Actions of Ethanol Extract of Camellia Sinensis Leaf Ameliorates Insulin Secretion, Inhibits the DPP-IV Enzyme, Improves Glucose Tolerance …

P Ansari, JMA Hannan, ST Choudhury, SS Islam… - Medicines, 2022 - mdpi.com
Camellia sinensis (green tea) is used in traditional medicine to treat a wide range of
ailments. In the present study, the insulin-releasing and glucose-lowering effects of the …

Demonstration of glycated insulin in human diabetic plasma and decreased biological activity assessed by euglycemic-hyperinsulinemic clamp technique in humans

SJ Hunter, AC Boyd, FPM O'Harte, AM McKillop… - Diabetes, 2003 - Am Diabetes Assoc
The presence and biological significance of circulating glycated insulin has been evaluated
by high-pressure liquid chromatography (HPLC), electrospray ionization mass spectrometry …

[HTML][HTML] The balance between gluco-and mineralo-corticoid action critically determines inflammatory adipocyte responses

J Hoppmann, N Perwitz, B Meier… - Journal of …, 2010 - joe.bioscientifica.com
This study was conducted to evaluate the responsiveness of human nonpregnant
myometrium to endothelin 1 (ET1)(10 (-10) M-10 (-6) M) and KCl (80 mM) in relation to the …