Selective progesterone receptor modulators (SPRMs) are a new class of compounds
developed to target the progesterone receptor (PR) with a mix of agonist and antagonist …

Background Pictorial blood loss assessment charts (PBACs) represent the most widely used
method to assess menstrual blood loss (MBL) in clinical trials. The aims of this review were …

Background Uterine fibroids are hormone-responsive neoplasms that are associated with
heavy menstrual bleeding. Elagolix, an oral gonadotropin-releasing hormone antagonist …

Progesterone receptors (PRs) are implicated in various cancers since their
presence/absence can determine clinical outcomes. The overstimulation of progesterone …

Uterine fibroids (leiomyomas or myomas) are the most frequent benign tumors in women.
Heavy menstrual bleeding with resultant anemia, dysmenorrhea, chronic pelvic pain …

Uterine fibroids are common in women of reproductive age and can have a significant
impact on quality of life and fertility. Although a number of international …

Introduction Uterine fibroids are the most common benign gynecological tumors affecting
women of reproductive ages. Although surgery is the definitive treatment choice, several …

В книге рассматриваются современные взгляды о роли генетических, эндокринных и
иммунологических факторов в патогенезе генитального эндометриоза, обсуждаются …

Uterine fibroids are the most common benign neoplasm of the female reproductive tract in
reproductive age women. Their prevalence is age dependent and can be detected in up to …

Objectives To assess the safety and efficacy of four vilaprisan doses (0.5–4.0 mg) in women
with uterine fibroids. Design Randomized, double-blind, placebo-controlled, multicenter trial …