Pre-eclampsia is a multisystem pregnancy disorder characterised by variable degrees of
placental malperfusion, with release of soluble factors into the circulation. These factors …

Vitamin D is essential for calcium and bone homeostasis. Humans are largely dependent on
UVB-radiation-induced photosynthesis of vitamin D, as few foods contain vitamin D …

A worldwide high prevalence of vitamin D (VD) deficiency has become of growing concern
because of potential adverse effects on human health, including pregnant women and their …

Background Vitamin D deficiency or insufficiency is thought to be common among pregnant
women. Vitamin D supplementation during pregnancy has been suggested as an …

Pregnancy-induced hypertension (PIH) complicates 6–10% of pregnancies. It is defined as
systolic blood pressure (SBP)> 140 mmHg and diastolic blood pressure (DBP)> 90 mmHg. It …

Vitamin D deficiency is common and there exists a huge gap between recommended dietary
vitamin D intakes and the poor vitamin D supply in the general population. While vitamin D is …

Pregnancy-induced hypertensive disorders can lead to maternal and perinatal morbidity and
mortality, but the cause of these conditions is not well understood. We have systematically …

BACKGROUND. Low vitamin D status in pregnancy was proposed as a risk factor of
preeclampsia. METHODS. We assessed the effect of vitamin D supplementation (4,400 vs …

Observational studies, randomized controlled trials (RCTs), and Mendelian randomization
(MR) studies have yielded inconsistent results on the associations of vitamin D …

Background Vitamin D deficiency during pregnancy increases the risk of pre‐eclampsia,
gestational diabetes, preterm birth, and low birthweight. In a previous Cochrane Review we …