Growing evidence suggests that vitamin C supplementation may be an effective adjunct
therapy in the management of people with diabetes. This paper critically reviews the current …

Reactive oxygen species (ROS) are well known for their role in insulin resistance and the
development of cardiometabolic disease including type 2 diabetes mellitus (T2D) …

This review summarizes recent knowledge about the use of the amino acid l-Cysteine (l-
Cys) through diet, nutritional supplements or drugs with the aim to improve human health or …

Oxidative stress and redox status play a central role in the link between insulin resistance
(IR) and lipotoxicity in metabolic syndrome. This mechanistic link may involve alterations in …

Metabolic syndrome, characterized by central obesity, hypertension, and hyperlipidemia,
increases the morbidity and mortality of cardiovascular disease, type 2 diabetes …

Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders in
women of both developed and developing countries. It is associated with insulin resistance …

Elevated levels of plasma free fatty acids (FFA), which are commonly found in obesity,
induce insulin resistance. FFA activate protein kinases including the proinflammatory IκBα …

NLRP3 inflammasome has a key role in chronic low-grade metabolic inflammation, and its
excessive activation may contribute to the beginning and progression of several diseases …

The aim of this research was to examine the clinical characteristics of acute kidney injury
(AKI) in primary nephrotic syndrome (NS) and discuss the relationship between serum lipids …

The mechanisms whereby prolonged plasma free fatty acids elevation, as found in obesity,
causes hepatic insulin resistance are not fully clarified. We herein investigated whether …