Clostridium perfringens causes many different histotoxic and enterotoxic diseases in
humans and animals as a result of its ability to produce potent protein toxins, many of which …

Clostridium perfringens uses its arsenal of> 16 toxins to cause histotoxic and intestinal
infections in humans and animals. It has been unclear why this bacterium produces so many …

Gram-negative and Gram-positive bacteria have evolved elaborate machinery to
biosynthesize and respond to diverse small-molecule signals. As bacteria grow, these …

For over 30 years a phospholipase C enzyme called alpha-toxin was thought to be the key
virulence factor in necrotic enteritis caused by Clostridium perfringens. However, using a …

Clostridium perfringens is a Gram-positive anaerobic spore-forming bacterium that causes
life-threatening gas gangrene and mild enterotoxaemia in humans, although it colonizes as …

In both humans and animals, Clostridium perfringens is an important cause of histotoxic
infections and diseases originating in the intestines, such as enteritis and enterotoxemia …

Virtually all bacterial pathogens require iron to infect vertebrates. The most abundant source
of iron within vertebrates is in the form of heme as a cofactor of hemoproteins. Many …

The regulation of competence for genetic transformation in Streptococcus pneumoniae
depends on a quorum‐sensing system, but the only molecular elements of the system …

Signal transduction in microorganisms and plants is often mediated by His–Asp
phosphorelay systems. Two conserved families of proteins are centrally involved: histidine …

▪ Abstract Clostridium perfringens causes human gas gangrene and food poisoning as well
as several enterotoxemic diseases of animals. The organism is characterized by its ability to …