[HTML][HTML] Signaling pathways and intervention therapies in sepsis
Y Zhang, B Ning - Signal Transduction and Targeted Therapy, 2021 - nature.com
Sepsis is defined as life-threatening organ dysfunction caused by dysregulated host
systemic inflammatory and immune response to infection. Over decades, advanced …
systemic inflammatory and immune response to infection. Over decades, advanced …
The immunopathology of sepsis and potential therapeutic targets
T van der Poll, FL van de Veerdonk… - Nature Reviews …, 2017 - nature.com
Sepsis is defined as a life-threatening organ dysfunction that is caused by a dysregulated
host response to infection. In sepsis, the immune response that is initiated by an invading …
host response to infection. In sepsis, the immune response that is initiated by an invading …
[HTML][HTML] Sepsis and septic shock
RS Hotchkiss, LL Moldawer, SM Opal… - Nature reviews Disease …, 2016 - nature.com
For more than two decades, sepsis was defined as a microbial infection that produces fever
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …
(or hypothermia), tachycardia, tachypnoea and blood leukocyte changes. Sepsis is now …
Innovative and rapid antimicrobial susceptibility testing systems
Antimicrobial resistance (AMR) is a major threat to human health worldwide, and the rapid
detection and quantification of resistance, combined with antimicrobial stewardship, are key …
detection and quantification of resistance, combined with antimicrobial stewardship, are key …
[HTML][HTML] Futuristic non-antibiotic therapies to combat antibiotic resistance: A review
The looming problem of resistance to antibiotics in microorganisms is a global health
concern. The drug-resistant microorganisms originating from anthropogenic sources and …
concern. The drug-resistant microorganisms originating from anthropogenic sources and …
Macrophage-like nanoparticles concurrently absorbing endotoxins and proinflammatory cytokines for sepsis management
S Thamphiwatana, P Angsantikul… - Proceedings of the …, 2017 - National Acad Sciences
Sepsis, resulting from uncontrolled inflammatory responses to bacterial infections, continues
to cause high morbidity and mortality worldwide. Currently, effective sepsis treatments are …
to cause high morbidity and mortality worldwide. Currently, effective sepsis treatments are …
An enzyme‐mimicking single‐atom catalyst as an efficient multiple reactive oxygen and nitrogen species scavenger for sepsis management
Sepsis, characterized by immoderate production of multiple reactive oxygen and nitrogen
species (RONS), causes high morbidity and mortality. Despite progress made with …
species (RONS), causes high morbidity and mortality. Despite progress made with …
Microfluidic devices: a tool for nanoparticle synthesis and performance evaluation
The use of nanoparticles (NPs) in nanomedicine holds great promise for the treatment of
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
diseases for which conventional therapies present serious limitations. Additionally, NPs can …
[HTML][HTML] based synthetic gene networks
Synthetic gene networks have wide-ranging uses in reprogramming and rewiring
organisms. To date, there has not been a way to harness the vast potential of these networks …
organisms. To date, there has not been a way to harness the vast potential of these networks …
A bioinspired omniphobic surface coating on medical devices prevents thrombosis and biofouling
Thrombosis and biofouling of extracorporeal circuits and indwelling medical devices cause
significant morbidity and mortality worldwide. We apply a bioinspired, omniphobic coating to …
significant morbidity and mortality worldwide. We apply a bioinspired, omniphobic coating to …