[HTML][HTML] Molecular mechanisms driving progression of liver cirrhosis towards hepatocellular carcinoma in chronic hepatitis B and C infections: a review

T Kanda, T Goto, Y Hirotsu, M Moriyama… - International journal of …, 2019 - mdpi.com
Almost all patients with hepatocellular carcinoma (HCC), a major type of primary liver
cancer, also have liver cirrhosis, the severity of which hampers effective treatment for HCC …

Clustered miRNAs and their role in biological functions and diseases

SP Kabekkodu, V Shukla, VK Varghese… - Biological …, 2018 - Wiley Online Library
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …

[HTML][HTML] Interaction and cross-talk between non-coding RNAs

S Yamamura, M Imai-Sumida, Y Tanaka… - Cellular and molecular …, 2018 - Springer
Non-coding RNA (ncRNA) has been shown to regulate diverse cellular processes and
functions through controlling gene expression. Long non-coding RNAs (lncRNAs) act as a …

[HTML][HTML] Long noncoding RNA MALAT1 in exosomes drives regenerative function and modulates inflammation-linked networks following traumatic brain injury

NA Patel, LD Moss, JY Lee, N Tajiri, S Acosta… - Journal of …, 2018 - Springer
Background Neuroinflammation is a common therapeutic target for traumatic brain injury
(TBI) due to its contribution to delayed secondary cell death and has the potential to occur …

[PDF][PDF] Stabilization of lncRNA GAS5 by a small molecule and its implications in diabetic adipocytes

Y Shi, S Parag, R Patel, A Lui, M Murr, J Cai… - Cell chemical …, 2019 - cell.com
Long noncoding RNA (lncRNA) are regulatory RNAs> 200 nt. We previously showed that
lncRNA GAS5 decreases significantly in serum of type 2 diabetes mellitus (T2DM) patients …

[HTML][HTML] Ftx non coding RNA-derived miR-545 promotes cell proliferation by targeting RIG-I in hepatocellular carcinoma

Z Liu, C Dou, B Yao, M Xu, L Ding, Y Wang, Y Jia, Q Li… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the third cause of cancer-related death worldwide.
Accumulating studies have demonstrated that aberrant expression of several lncRNAs was …

Gender disparity in hepatocellular carcinoma (HCC): multiple underlying mechanisms

B Zheng, YJ Zhu, HY Wang, L Chen - Science China Life Sciences, 2017 - Springer
On the global scale, hepatitis B virus (HBV) infection is the main cause of hepatocellular
carcinoma (HCC) especially in regions of Asia where HBV infection is endemic …

[HTML][HTML] lncRNA Ftx promotes aerobic glycolysis and tumor progression through the PPARγ pathway in hepatocellular carcinoma

X Li, Q Zhao, J Qi, W Wang… - … journal of oncology, 2018 - spandidos-publications.com
Aerobic glycolysis is a phenomenon by which malignant cells preferentially metabolize
glucose through the glycolytic pathway, rather than oxidative phosphorylation to proliferate …

[HTML][HTML] The regulatory role of microRNA in hepatitis-B virus-associated hepatocellular carcinoma (HBV-HCC) pathogenesis

K Sartorius, J Makarova, B Sartorius, P An, C Winkler… - Cells, 2019 - mdpi.com
The incidence and mortality of hepatitis B virus (HBV)-associated hepatocellular carcinoma
(HBV-HCC) is an intractable public health problem in developing countries that is …

Extracellular vesicle long noncoding RNA as potential biomarkers of liver cancer

S Mohankumar, T Patel - Briefings in functional genomics, 2016 - academic.oup.com
Abstract Analysis of extracellular vesicles (EV) and their contents may be useful as disease
biomarkers if they reflect the contents of cells of origin, differ between normal and diseased …