The basal position of fish in vertebrate phylogeny makes them very attractive for genomic
and functional comparative immunity studies. Adaptive immunity arose early in vertebrate …

Starting out as a model for developmental biology, during the last decade, zebrafish have
also gained the attention of the immunologists and oncologists. Due to its small size, high …

Teleosts clearly have a more diffuse gut associated lymphoid system, which is
morphological and functional clearly different from the mammalian GALT. All immune cells …

Mast cells and basophils are potent effector cells of the innate immune system, and they
have both beneficial and detrimental functions for the host. They are mainly implicated in pro …

Since its first splash 30 years ago, the use of the zebrafish model has been extended from a
tool for genetic dissection of early vertebrate development to the functional interrogation of …

The zebrafish (Danio rerio) has been extensively used in biomedical research as a model to
study vertebrate development and hematopoiesis and recently, it has been adopted into …

The zebrafish holds much promise as a high-throughput drug screening model for immune-
related diseases, including inflammatory and infectious diseases and cancer. This is due to …

The zebrafish has become a powerful vertebrate model for genetic studies of embryonic
development and organogenesis and increasingly for studies in cancer biology. Zebrafish …

In mammals, dendritic cells (DCs) form the key link between the innate and adaptive
immune systems. DCs act as immune sentries in various tissues and, upon encountering …

The common goldfish is the most widespread teleosts in the world. Due to its peculiar
characteristics, such as the high resistance, easy availability and stabulation, and for its …