Mitochondrial dysfunction, oxidative stress, neuroinflammation, and metabolic alterations in the progression of Alzheimer's disease: A meta-analysis of in vivo …

T Song, X Song, C Zhu, R Patrick, M Skurla… - Ageing research …, 2021 - Elsevier
Accumulating evidence demonstrates that metabolic changes in the brain associated with
neuroinflammation, oxidative stress, and mitochondrial dysfunction play an important role in …

[HTML][HTML] Oxidant/antioxidant imbalance in Alzheimer's disease: therapeutic and diagnostic prospects

J Wojsiat, KM Zoltowska… - … medicine and cellular …, 2018 - hindawi.com
Alzheimer's disease (AD) is the most common cause of dementia and a great
socioeconomic burden in the aging society. Compelling evidence demonstrates that …

Brain glutathione levels–a novel biomarker for mild cognitive impairment and Alzheimer's disease

PK Mandal, S Saharan, M Tripathi, G Murari - Biological psychiatry, 2015 - Elsevier
Background Extant data from in vivo animal models and postmortem studies indicate that
Alzheimer's disease (AD) pathology is associated with reduction of the brain antioxidant …

Metal dyshomeostasis and oxidative stress in Alzheimer's disease

MA Greenough, J Camakaris, AI Bush - Neurochemistry international, 2013 - Elsevier
Alzheimer's disease is the leading cause of dementia in the elderly and is defined by two
pathological hallmarks; the accumulation of aggregated amyloid beta and excessively …

[HTML][HTML] Glycolytic metabolism, brain resilience, and Alzheimer's disease

X Zhang, N Alshakhshir, L Zhao - Frontiers in Neuroscience, 2021 - frontiersin.org
Alzheimer's disease (AD) is the most common form of age-related dementia. Despite
decades of research, the etiology and pathogenesis of AD are not well understood. Brain …

[HTML][HTML] Molecular mechanisms and genetics of oxidative stress in Alzheimer's disease

F Cioffi, RHI Adam, K Broersen - Journal of Alzheimer's …, 2019 - content.iospress.com
Alzheimer's disease is the most common neurodegenerative disorder that can cause
dementia in elderly over 60 years of age. One of the disease hallmarks is oxidative stress …

[HTML][HTML] The Therapeutic Potential of Rosemary (Rosmarinus officinalis) Diterpenes for Alzheimer's Disease

S Habtemariam - Evidence-Based Complementary and Alternative …, 2016 - hindawi.com
Rosemary (Rosmarinus officinalis L.) is one of the most economically important species of
the family Lamiaceae. Native to the Mediterranean region, the plant is now widely distributed …

Antioxidant activity of sulfur and selenium: a review of reactive oxygen species scavenging, glutathione peroxidase, and metal-binding antioxidant mechanisms

EE Battin, JL Brumaghim - Cell biochemistry and biophysics, 2009 - Springer
It is well known that oxidation caused by reactive oxygen species (ROS) is a major cause of
cellular damage and death and has been implicated in cancer, neurodegenerative, and …

Oxidative stress in blood in Alzheimer's disease and mild cognitive impairment: a meta-analysis

M Schrag, C Mueller, M Zabel, A Crofton… - Neurobiology of …, 2013 - Elsevier
Abnormal oxidative stress is an established feature of Alzheimer's disease, but clinical trials
aiming to reduce oxidative stress have not yet proven an effective therapy for dementia …

[HTML][HTML] Ferroptosis, a potential therapeutic target in Alzheimer's disease

K Chen, X Jiang, M Wu, X Cao, W Bao… - Frontiers in Cell and …, 2021 - frontiersin.org
Cell death is a common phenomenon in the progression of Alzheimer's disease (AD).
However, the mechanism of triggering the death of neuronal cells remains unclear …