Mortality from colorectal cancer is reduced through screening and early detection; moreover,
removal of neoplastic lesions can reduce cancer incidence. While understanding of the risk …

In the past decades the incidence of colorectal cancer (CRC) in people under the age of 50
years has increased, which is referred to as early-onset CRC or young-onset CRC (YO …

Colorectal cancer (CRC), a leading cause of cancer-related death worldwide, evolves as a
result of the stepwise accumulation of a series of genetic and epigenetic alterations in the …

Following initial successes in melanoma treatment, immunotherapy has rapidly become
established as a major treatment modality for multiple types of solid cancers, including a …

Abstract Each year, the American Cancer Society publishes a summary of its guidelines for
early cancer detection, data and trends in cancer screening rates, and select issues related …

Abstract In the United States, colorectal cancer (CRC) is the fourth most common cancer
diagnosed among adults and the second leading cause of death from cancer. For this …

Colonoscopy is performed routinely for colorectal cancer (CRC) screening, follow-up of
other abnormal screening tests, workup of signs and symptoms of gastrointestinal disease …

The incidence of early-onset colorectal cancer (CRC), which occurs in individuals< 50 years
of age, has been increasing worldwide and particularly in high-income countries. The …

Abstract Each year, the American Cancer Society publishes a summary of its guidelines for
early cancer detection, data and trends in cancer screening rates from the National Health …

Purpose Microsatellite instability (MSI) is a pattern of hypermutation that occurs at genomic
microsatellites and is caused by defects in the mismatch repair system. Mismatch repair …