Growth hormone (GH) research and its clinical application for the treatment of growth
disorders span more than a century. During the first half of the 20th century, clinical …

Growth hormone (GH) has been used for over 35 years, and its safety and efficacy has been
studied extensively. Experimental studies showing the permissive role of GH/insulin-like …

Context: Measurement of IGF-I is a cornerstone in diagnosis and monitoring of GH-related
diseases, but considerable discrepancies exist between analytical methods. A recent …

Hypopituitarism refers to deficiency of one or more hormones produced by the anterior
pituitary or released from the posterior pituitary. Hypopituitarism is associated with excess …

Objective: The development of these guidelines is sponsored by the American Association
of Clinical Endocrinologists (AACE) Board of Directors and American College of …

Objective: Our objective was to summarize important advances in the management of
children with idiopathic short stature (ISS). Participants: Participants were 32 invited leaders …

Recombinant human GH (rhGH) has been in use for 30 years, and over that time its safety
and efficacy in children and adults has been subject to considerable scrutiny. In 2001, a …

Abstract Growth hormone (GH), insulin-like growth factor (IGF)-I and insulin have potent
growth-promoting and anabolic actions. Their potential involvement in tumor promotion and …

Growth hormone (GH) and insulin-like growth factor I (IGF-I) measurements are widely used
in the diagnosis of disorders of GH secretion, evaluation of children with short stature from …

Obesity is a serious public health issue and associated with an increased risk of
cardiovascular disease events and mortality. The risk of cardiovascular complications is …