The development of new methods for the direct functionalization of unactivated C–H bonds
is ushering in a paradigm shift in the field of retrosynthetic analysis. In particular, the catalytic …

Conspectus The oxindole scaffold is a privileged structural motif that is found in a variety of
bioactive targets and natural products. Moreover, derivatives of the oxindole structure are …

The enantioselective synthesis of molecules containing quaternary stereocenters is a field of
intense research interest and development. Among the known organic transformations …

Reductive carboxylation of organo (pseudo) halides with CO2 is a powerful method to
provide carboxylic acids quickly. Notably, the catalytic reductive carbo‐carboxylation of …

Abstract The 3, 3′‐disubstituted oxindole structural motif is a prominent feature in many
alkaloid natural products, which include all kinds of tetrasubstituted carbon stereocenters …

The palladium-catalyzed cyanation of Ar–X (X= I, Br, Cl, OTf, and H) allows for an efficient
access towards benzonitriles. After its discovery in 1973 and following significant …

The Pd (0)-catalyzed vinylation of aryl halides was first reported over 30 years ago in
independent studies by Mizoroki and Heck. 1 The transformation that has come to be known …

Abstract Silver screen: The AgNO3‐catalyzed carbon phosphorylation of alkenes occurs by
an alkene addition/cyclization cascade. Ag+ reacts with Ph2P (O) H to form the crucial active …

Oxindoles are important heterocycles found in a wide range of bioactive natural products
and pharmaceutical molecules.[1, 2] In addition, functionalized oxindoles are versatile …

Research on natural products containing hexahydropyrrolo [2, 3‐b] indole (HPI) has
dramatically increased during the past few years. Newly discovered natural products with …