[HTML][HTML] Hypoxia-Inducible Factor and Oxidative Stress in Tendon Degeneration: A Molecular Perspective

H Shahid, VK Morya, JU Oh, JH Kim, KC Noh - Antioxidants, 2024 - mdpi.com
Tendinopathy is a debilitating condition marked by degenerative changes in the tendons. Its
complex pathophysiology involves intrinsic, extrinsic, and physiological factors. While its …

The impact of type 2 diabetes on the development of tendinopathy

F Cannata, G Vadalà, L Ambrosio… - Diabetes/Metabolism …, 2021 - Wiley Online Library
Tendinopathy is a chronic and often painful condition affecting both professional athletes
and sedentary subjects. It is a multi‐etiological disorder caused by the interplay among …

[HTML][HTML] Does vancomycin wrapping in anterior cruciate ligament reconstruction affect tenocyte activity in vitro?

R Papalia, C Cicione, F Russo, L Ambrosio… - Antibiotics, 2021 - mdpi.com
Knee septic arthritis is a devastating complication following anterior cruciate ligament (ACL)
reconstruction. To prevent this issue, intraoperative soaking of ACL grafts with vancomycin is …

[PDF][PDF] Pharmacological interventions for the treatment of Achilles tendinopathy: a systematic review of randomized controlled trials

N Maffulli, R Papalia, S D'Adamio, L Diaz Balzani… - Br Med Bull, 2015 - researchgate.net
Introduction: Several pharmacological interventions have been proposed for the
management of Achilles tendinopathy, with no agreement on which is the overall best option …

[HTML][HTML] Role of VEGF, nitric oxide, and sympathetic neurotransmitters in the pathogenesis of tendinopathy: A review of the current evidences

S Vasta, A Di Martino, B Zampogna, G Torre… - Frontiers in Aging …, 2016 - frontiersin.org
Chronic tendinopathy is a painful common condition affecting athletes as well as the general
population undergoing to tendon overuse. Although its huge prevalence, little is known …

Effects of isometric loading intensity on patellar tendon microvascular response

JE Earp, H Gesick, D Angelino… - Scandinavian journal of …, 2022 - Wiley Online Library
Acute increases in tendon blood flow and oxygenation after stress (ie, hyperemic response)
can enhance tendon recovery. While loading intensity is a fundamental part of resistance …

Effect of cilostazol on healing of achilles tendon ruptures: an experimental study on rats

B Yılmaz, O Kose, N Karahan… - Connective Tissue …, 2024 - Taylor & Francis
Purpose This study aimed to evaluate whether cilostazol (phosphodiesterase III inhibitor)
could enhance the healing of Achilles tendon ruptures in rats. Materials and methods The …

Human tendon-on-a-chip for modeling vascular inflammatory fibrosis

H Awad, R Ajalik, R Alenchery, I Linares, T Wright… - 2023 - researchsquare.com
Understanding vascular inflammation and myofibroblast crosstalk is critical to developing
therapies for fibrotic diseases. Here we report the development of a novel human Tendon-on …

[HTML][HTML] Optimizing repair of tendon ruptures and chronic tendinopathies: Integrating the use of biomarkers with biological interventions to improve patient outcomes …

DA Hart, AS Ahmed, P Ackermann - Frontiers in Sports and Active …, 2023 - frontiersin.org
Tendons are dense connective tissues of the musculoskeletal system that link bones with
muscles to foster mobility. They have complex structures and exist in varying biomechanical …

Is there a role for endothelial dysfunction in the pathogenesis of lumbar disc degeneration? A hypothesis that needs to be tested

R Papalia, E Albo, G Vadalà, S D'Adamio, A Lanotte… - Medical hypotheses, 2015 - Elsevier
Low back pain is a painful condition affecting most people at least once in their life. It can be
the expression of lumbar disc degeneration, a condition whose progression is influenced by …