Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths
worldwide. Underlying chronic liver disease has been associated with an increased risk of …

Cholangiocarcinoma (CCA) is the most common malignancy in patients with primary
sclerosing cholangitis (PSC) and carries a high rate of mortality. Although the pathogenesis …

Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are human
primary cholangiopathies characterized by the damage of mature cholangiocytes and by the …

Simple Summary Here we show that a protein called C/EBPδ is present in healthy pancreas
tissue but almost absent in pancreas tumors. Patients with less C/EBPδ in their tumors had …

Results Based on prediction and validation, miR-26a was inversely correlated with KRT19 in
patients' tissues samples and biopsies. Ectopic expression of miR-26a dramatically …

Background A distinct serum metabonomic pattern has been previously revealed to be
associated with various forms of liver disease. Here, we aimed to apply mass spectrometry …

Primary biliary cholangitis (PBC) is a progressive inflammatory disorder that results in
cholestasis. PBC can lead to clinical consequences related to chronic cholestasis that affect …

Abstract α7-nAChR is a nicotinic acetylcholine receptor [specifically expressed on hepatic
stellate cells (HSCs), Kupffer cells, and cholangiocytes] that regulates inflammation and …

Objectives/Hypothesis Probe‐based confocal laser endomicroscopy (pCLE) is a novel
technique allowing real‐time evaluation of the histological features of tissues in vivo at the …

In this study, we investigated the role of tumor microenvironment and serum differential
metabolites in intrahepatic cholangiocarcinoma (ICC) carcinogenesis, providing new …