Fucoidan in pharmaceutical formulations: a comprehensive review for smart drug delivery systems
Fucoidan is a heterogeneous group of polysaccharides isolated from marine organisms,
including brown algae and marine invertebrates. The physicochemical characteristics and …
including brown algae and marine invertebrates. The physicochemical characteristics and …
[HTML][HTML] The two faces of the integrated stress response in cancer progression and therapeutic strategies
E Licari, L Sánchez-del-Campo, P Falletta - The International Journal of …, 2021 - Elsevier
In recent years considerable progress has been made in identifying the impact of mRNA
translation in tumour progression. Cancer cells hijack the pre-existing translation machinery …
translation in tumour progression. Cancer cells hijack the pre-existing translation machinery …
Coriander (Coriandrum sativum L.) essential oil and oil-loaded nano-formulations as an anti-aging potentiality via TGFβ/SMAD pathway
Aging has become a concern for many people, especially women. Given that high-quality
anti-aging products are of high cost; it has imperative to search for other economical …
anti-aging products are of high cost; it has imperative to search for other economical …
pH-sensitive nanoparticles containing 5-fluorouracil and leucovorin as an improved anti-cancer option for colon cancer
Background: Parenteral administration of chemotherapeutic drugs, 5-fluorouracil (5-FU) and
leucovorin (LV), is commonly used to treat large bowel carcinomas such as colon cancer …
leucovorin (LV), is commonly used to treat large bowel carcinomas such as colon cancer …
Cell-penetrating peptide-modified graphene oxide nanoparticles loaded with rictor siRNA for the treatment of triple-negative breast cancer
YY Yang, W Zhang, H Liu, JJ Jiang… - Drug design …, 2021 - Taylor & Francis
Introduction Breast cancer is a malignant tumor that seriously threatens women's life and
health. Methods In this study, we proposed to use graphene nanoparticles loaded with …
health. Methods In this study, we proposed to use graphene nanoparticles loaded with …
Ros-responsive galactosylated-nanoparticles with doxorubicin entrapment for triple negative breast cancer therapy
J Zhou, K Li, X Zang, Y Xie, J Song… - International Journal of …, 2023 - Taylor & Francis
Background Triple negative breast cancer (TNBC) is one of the most aggressive tumors with
high metastasis and mortality, which constitutes 15~ 20% of all breast cancers …
high metastasis and mortality, which constitutes 15~ 20% of all breast cancers …
Photothermal therapy mediated hybrid membrane derived nano-formulation for enhanced cancer therapy
X Cao, T Deng, Q Zhu, J Wang, W Shi, Q Liu, Q Yu… - AAPS …, 2023 - Springer
Emodin is applied as an antitumor drug in many tumor therapies. However, its
pharmacology performances are limited due to its low solubility. Herein, we fused …
pharmacology performances are limited due to its low solubility. Herein, we fused …
Multifunctional nanoplatform-mediated chemo-photothermal therapy combines immunogenic cell death with checkpoint blockade to combat triple-negative breast …
H Zhu, K Yang, H Yao, X Chen, S Yan… - International Journal …, 2023 - Taylor & Francis
Background Breast cancer has become the most common cancer in women. Compare with
other subtypes of breast cancer, triple-negative breast cancer (TNBC) is more likely to …
other subtypes of breast cancer, triple-negative breast cancer (TNBC) is more likely to …
Polymeric micro/nanocarriers and motors for cargo transport and phototriggered delivery
P Mena-Giraldo, J Orozco - Polymers, 2021 - mdpi.com
Smart polymer-based micro/nanoassemblies have emerged as a promising alternative for
transporting and delivering a myriad of cargo. Cargo encapsulation into (or linked to) …
transporting and delivering a myriad of cargo. Cargo encapsulation into (or linked to) …
Clinical pharmacology of siRNA therapeutics: current status and future prospects
ABSTRACT Introduction Small interfering RNA (siRNA) has emerged as a powerful tool for
post-transcriptional downregulation of multiple genes for various therapies. Naked siRNA …
post-transcriptional downregulation of multiple genes for various therapies. Naked siRNA …