Growing evidence supports the concept that Alzheimer's disease (AD) is fundamentally a
metabolic disease with molecular and biochemical features that correspond with diabetes …

Like most organ systems throughout the body, the brain requires insulin and insulinlike
growth factors (IGFs) to maintain energy metabolism, cell survival, and homeostasis. In …

BACKGROUND: Weight gain and increased production of leptin may be associated with
immuno-modulation and insulin resistance in bipolar disorder. The links among …

Background: Chronic kidney disease (CKD) is associated with increased risk for
cardiovascular (CV) disease and is also associated with elevated uric acid, which is …

Non-alcoholic fatty liver disease (NAFLD) and alcoholic liver disease (ALD) are among the
most common causes of chronic liver diseases in the westernized world. NAFLD and ALD …

Background Insulin resistance (IR) assessed by the Homeostatic Model Assessment
(HOMA) index in the acute phase of myocardial infarction in non-diabetic patients was …

Diabetes mellitus (DM), a metabolic disorder is a major orchestra influencing brain and
behavioral responses via direct or indirect mechanisms. Many lines of evidence suggest that …

Introducción Las alteraciones en el metabolismo de la glucosa son un factor de riesgo y de
peor pronóstico para infarto agudo de miocardio (IAM), pero esta información en población …

Clinical glucocorticoid use, and diseases that produce elevated circulating glucocorticoids,
promote drastic changes in body composition and reduction in whole body insulin …

Background: Despite optimal treatment, type II diabetes mellitus remains associated with an
increased risk for future cardiovascular events. We sought to determine the association …