Abstract Background/Aims: On behalf of the Drug and Therapeutics, and Ethics Committees
of the Pediatric Endocrine Society, we sought to update the guidelines published in 2003 on …

Acromegaly is a chronic systemic disease with many complications and is associated with
increased mortality when not adequately treated. Substantial advances in acromegaly …

Growth hormone (GH) has been used for over 35 years, and its safety and efficacy has been
studied extensively. Experimental studies showing the permissive role of GH/insulin-like …

Hypopituitarism refers to deficiency of one or more hormones produced by the anterior
pituitary or released from the posterior pituitary. Hypopituitarism is associated with excess …

Objective: The aim was to update The Endocrine Society Clinical Practice Guideline on
Evaluation and Treatment of Adult Growth Hormone Deficiency (GHD) previously published …

Objective: The development of these guidelines is sponsored by the American Association
of Clinical Endocrinologists (AACE) Board of Directors and American College of …

Growth hormone (GH) deficiency (GHD) in children is defined as impaired production of GH
by the pituitary gland that results in growth failure. This disease might be congenital or …

Postnatal growth and development of the human body and its specific organs are regulated
by a complex network of local and systemic factors which is poorly understood. This review …

Incidence and prevalence of hypopituitarism are estimated to be 4· 2 per 100 000 per year
and 45· 5 per 100 000, respectively. Although the clinical symptoms of this disorder are …

Growth Hormone Assessment in Adults Growth hormone synthesis and physiology are
discussed in the context of recombinant growth hormone use in adults. Growth hormone …