From design to clinic: engineered nanobiomaterials for immune normalization therapy of cancer

M Saeed, F Chen, J Ye, Y Shi, T Lammers… - Advanced …, 2021 - Wiley Online Library
The tumor immune microenvironment (TIME) is comprised of a complex milieu that
contributes to stunting antitumor immune responses by restricting T cells to accumulate in …

Phylogenomics and the flowering plant tree of life

C Guo, Y Luo, LM Gao, TS Yi, HT Li… - Journal of Integrative …, 2023 - Wiley Online Library
The advances accelerated by next‐generation sequencing and long‐read sequencing
technologies continue to provide an impetus for plant phylogenetic study. In the past …

Plastid phylogenomic insights into relationships of all flowering plant families

HT Li, Y Luo, L Gan, PF Ma, LM Gao, JB Yang, J Cai… - BMC biology, 2021 - Springer
Background Flowering plants (angiosperms) are dominant components of global terrestrial
ecosystems, but phylogenetic relationships at the familial level and above remain only …

Chloranthus genome provides insights into the early diversification of angiosperms

X Guo, D Fang, SK Sahu, S Yang, X Guang… - Nature …, 2021 - nature.com
Chloranthales remain the last major mesangiosperm lineage without a nuclear genome
assembly. We therefore assemble a high-quality chromosome-level genome of Chloranthus …

TSEBRA: transcript selector for BRAKER

L Gabriel, KJ Hoff, T Brůna, M Borodovsky, M Stanke - Bmc Bioinformatics, 2021 - Springer
Background BRAKER is a suite of automatic pipelines, BRAKER1 and BRAKER2, for the
accurate annotation of protein-coding genes in eukaryotic genomes. Each pipeline trains …

Insights into angiosperm evolution, floral development and chemical biosynthesis from the Aristolochia fimbriata genome

L Qin, Y Hu, J Wang, X Wang, R Zhao, H Shan, K Li… - Nature Plants, 2021 - nature.com
Aristolochia, a genus in the magnoliid order Piperales, has been famous for centuries for its
highly specialized flowers and wide medicinal applications. Here, we present a new, high …

RIdeogram: drawing SVG graphics to visualize and map genome-wide data on the idiograms

Z Hao, D Lv, Y Ge, J Shi, D Weijers, G Yu… - PeerJ Computer …, 2020 - peerj.com
Background Owing to the rapid advances in DNA sequencing technologies, whole genome
from more and more species are becoming available at increasing pace. For whole-genome …

Deciphering chemical logic of fungal natural product biosynthesis through heterologous expression and genome mining

CY Chiang, M Ohashi, Y Tang - Natural Product Reports, 2023 - pubs.rsc.org
Covering: 2010 to 2022 Heterologous expression of natural product biosynthetic gene
clusters (BGCs) has become a widely used tool for genome mining of cryptic pathways …

The chromosome-level wintersweet (Chimonanthus praecox) genome provides insights into floral scent biosynthesis and flowering in winter

J Shang, J Tian, H Cheng, Q Yan, L Li, A Jamal, Z Xu… - Genome biology, 2020 - Springer
Abstract Background Wintersweet (Chimonanthus praecox), an important ornamental plant,
has evolved unique fragrant aroma and winter-flowering properties, which are critical for its …

[PDF][PDF] The chromosome-scale genome of Phoebe bournei reveals contrasting fates of terpene synthase (TPS)-a and TPS-b subfamilies

X Han, J Zhang, S Han, SL Chong, G Meng… - Plant …, 2022 - cell.com
Terpenoids, including aromatic volatile monoterpenoids and sesquiterpenoids, function in
defense against pathogens and herbivores. Phoebe trees are remarkable for their scented …