[HTML][HTML] COVID-19: unmasking emerging SARS-CoV-2 variants, vaccines and therapeutic strategies
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
the coronavirus disease 2019 (COVID-19) pandemic, which has been a topic of major …
the coronavirus disease 2019 (COVID-19) pandemic, which has been a topic of major …
[HTML][HTML] Glutathione S-transferase enzymes in plant-pathogen interactions
G Gullner, T Komives, L Király, P Schröder - Frontiers in plant science, 2018 - frontiersin.org
Plant glutathione S-transferases (GSTs) are ubiquitous and multifunctional enzymes
encoded by large gene families. A characteristic feature of GST genes is their high …
encoded by large gene families. A characteristic feature of GST genes is their high …
[PDF][PDF] A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins
Proteins such as FUS phase separate to form liquid-like condensates that can harden into
less dynamic structures. However, how these properties emerge from the collective …
less dynamic structures. However, how these properties emerge from the collective …
The 3.8 Å resolution cryo-EM structure of Zika virus
The recent rapid spread of Zika virus and its unexpected linkage to birth defects and an
autoimmune neurological syndrome have generated worldwide concern. Zika virus is a …
autoimmune neurological syndrome have generated worldwide concern. Zika virus is a …
PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities
N Đukić, Ø Strømland, JD Elsborg, D Munnur, K Zhu… - Science …, 2023 - science.org
PARP14 is a mono–ADP-ribosyl transferase involved in the control of immunity,
transcription, and DNA replication stress management. However, little is known about the …
transcription, and DNA replication stress management. However, little is known about the …
Experimental evidence for the functional importance and adaptive advantage of A-to-I RNA editing in fungi
K Xin, Y Zhang, L Fan, Z Qi, C Feng… - Proceedings of the …, 2023 - National Acad Sciences
Adenosine-to-inosine (A-to-I) editing is the most prevalent type of RNA editing in animals,
and it occurs in fungi specifically during sexual reproduction. However, it is debatable …
and it occurs in fungi specifically during sexual reproduction. However, it is debatable …
[HTML][HTML] Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
J Liu, ZX Liu, QN Wu, YX Lu, CW Wong, L Miao… - Nature …, 2020 - nature.com
Tumor cells often reprogram their metabolism for rapid proliferation. The roles of long
noncoding RNAs (lncRNAs) in metabolism remodeling and the underlying mechanisms …
noncoding RNAs (lncRNAs) in metabolism remodeling and the underlying mechanisms …
Zika virus structure, maturation, and receptors
The emergence of Zika virus (ZIKV) as a major public health threat has focused research on
understanding virus biology and developing a suite of strategies for disease intervention …
understanding virus biology and developing a suite of strategies for disease intervention …
Comprehensive characterization of three classes of Arabidopsis SWI/SNF chromatin remodelling complexes
J Guo, G Cai, YQ Li, YX Zhang, YN Su, DY Yuan… - Nature Plants, 2022 - nature.com
Although SWI/SNF chromatin remodelling complexes are known to regulate diverse
biological functions in plants, the classification, compositions and functional mechanisms of …
biological functions in plants, the classification, compositions and functional mechanisms of …
[PDF][PDF] Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer
Tumor mutational burden and heterogeneity has been suggested to fuel resistance to many
targeted therapies. The cytosine deaminase APOBEC proteins have been implicated in the …
targeted therapies. The cytosine deaminase APOBEC proteins have been implicated in the …