[HTML][HTML] COVID-19: unmasking emerging SARS-CoV-2 variants, vaccines and therapeutic strategies

R Raman, KJ Patel, K Ranjan - Biomolecules, 2021 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological agent of
the coronavirus disease 2019 (COVID-19) pandemic, which has been a topic of major …

[HTML][HTML] Glutathione S-transferase enzymes in plant-pathogen interactions

G Gullner, T Komives, L Király, P Schröder - Frontiers in plant science, 2018 - frontiersin.org
Plant glutathione S-transferases (GSTs) are ubiquitous and multifunctional enzymes
encoded by large gene families. A characteristic feature of GST genes is their high …

[PDF][PDF] A molecular grammar governing the driving forces for phase separation of prion-like RNA binding proteins

J Wang, JM Choi, AS Holehouse, HO Lee, X Zhang… - Cell, 2018 - cell.com
Proteins such as FUS phase separate to form liquid-like condensates that can harden into
less dynamic structures. However, how these properties emerge from the collective …

The 3.8 Å resolution cryo-EM structure of Zika virus

D Sirohi, Z Chen, L Sun, T Klose, TC Pierson… - Science, 2016 - science.org
The recent rapid spread of Zika virus and its unexpected linkage to birth defects and an
autoimmune neurological syndrome have generated worldwide concern. Zika virus is a …

PARP14 is a PARP with both ADP-ribosyl transferase and hydrolase activities

N Đukić, Ø Strømland, JD Elsborg, D Munnur, K Zhu… - Science …, 2023 - science.org
PARP14 is a mono–ADP-ribosyl transferase involved in the control of immunity,
transcription, and DNA replication stress management. However, little is known about the …

Experimental evidence for the functional importance and adaptive advantage of A-to-I RNA editing in fungi

K Xin, Y Zhang, L Fan, Z Qi, C Feng… - Proceedings of the …, 2023 - National Acad Sciences
Adenosine-to-inosine (A-to-I) editing is the most prevalent type of RNA editing in animals,
and it occurs in fungi specifically during sexual reproduction. However, it is debatable …

[HTML][HTML] Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming

J Liu, ZX Liu, QN Wu, YX Lu, CW Wong, L Miao… - Nature …, 2020 - nature.com
Tumor cells often reprogram their metabolism for rapid proliferation. The roles of long
noncoding RNAs (lncRNAs) in metabolism remodeling and the underlying mechanisms …

Zika virus structure, maturation, and receptors

D Sirohi, RJ Kuhn - The Journal of infectious diseases, 2017 - academic.oup.com
The emergence of Zika virus (ZIKV) as a major public health threat has focused research on
understanding virus biology and developing a suite of strategies for disease intervention …

Comprehensive characterization of three classes of Arabidopsis SWI/SNF chromatin remodelling complexes

J Guo, G Cai, YQ Li, YX Zhang, YN Su, DY Yuan… - Nature Plants, 2022 - nature.com
Although SWI/SNF chromatin remodelling complexes are known to regulate diverse
biological functions in plants, the classification, compositions and functional mechanisms of …

[PDF][PDF] Loss of SYNCRIP unleashes APOBEC-driven mutagenesis, tumor heterogeneity, and AR-targeted therapy resistance in prostate cancer

X Li, Y Wang, S Deng, G Zhu, C Wang, NA Johnson… - Cancer cell, 2023 - cell.com
Tumor mutational burden and heterogeneity has been suggested to fuel resistance to many
targeted therapies. The cytosine deaminase APOBEC proteins have been implicated in the …