Cancer cells are disordered by nature and thus featured by higher internal redox level than
healthy cells. Redox imbalance could trigger programmed cell death if exceeded a certain …

Artesunate (ART) is a derivative of artemisinin that is extracted from the wormwood plant
Artemisia annua. ART is an antimalarial drug that has been shown to be safe and effective …

Ferroptosis is closely linked to various cancers, including lung adenocarcinoma (LUAD);
however, the factors involved in the regulation of ferroptosis-related genes are not well …

Interleukin-4-induced-1 (IL4i1) is an amino acid oxidase secreted from immune cells. Recent
observations have suggested that IL4i1 is pro-tumorigenic via unknown mechanisms. As …

CircRNAs have garnered significant interest in recent years due to their regulation in human
tumorigenesis, yet, the function of most glioma-related circRNAs remains unclear. In this …

Sorafenib, a first-line molecular-target drug for advanced hepatocellular carcinoma (HCC),
has been shown to be a potent ferroptosis inducer in HCC. However, we found that there …

The gene expression profile of abdominal aortic aneurysm (AAA) neck is not fully
understood. The etiology of AAA is considered to be related to atherosclerosis and the …

Hepatocellular carcinoma (HCC) is highly malignant and prone to metastasize due to the
heterogeneous and immunosuppressive tumor microenvironment (TME). Programmed cell …

Clear cell renal cell carcinoma (ccRCC) is one of the tumor types with sensitivity to
ferroptosis, and immunotherapy has emerged as a standard pillar for metastatic ccRCC …

Solid tumors have developed robust ferroptosis resistance. The mechanism underlying
ferroptosis resistance regulation in solid tumors, however, remains elusive. Here, we report …