Lung cancer screening, version 3.2018, NCCN clinical practice guidelines in oncology
Lung cancer is the leading cause of cancer-related mortality in the United States and
worldwide. Early detection of lung cancer is an important opportunity for decreasing …
worldwide. Early detection of lung cancer is an important opportunity for decreasing …
A decade of GWAS results in lung cancer
Genome-wide association studies (GWAS) were successful to identify genetic factors
robustly associated with lung cancer. This review aims to synthesize the literature in this field …
robustly associated with lung cancer. This review aims to synthesize the literature in this field …
Identification of susceptibility pathways for the role of chromosome 15q25. 1 in modifying lung cancer risk
Genome-wide association studies (GWAS) identified the chromosome 15q25. 1 locus as a
leading susceptibility region for lung cancer. However, the pathogenic pathways, through …
leading susceptibility region for lung cancer. However, the pathogenic pathways, through …
α9‐and α7‐containing receptors mediate the pro‐proliferative effects of nicotine in the A549 adenocarcinoma cell line
V Mucchietto, F Fasoli, S Pucci… - British journal of …, 2018 - Wiley Online Library
Background and Purpose Tobacco smoke contains many classes of carcinogens and
although nicotine is unable to initiate tumourigenesis in humans and rodents, it promotes …
although nicotine is unable to initiate tumourigenesis in humans and rodents, it promotes …
The daunting polygenicity of mental illness: making a new map
SE Hyman - … Transactions of the Royal Society B …, 2018 - royalsocietypublishing.org
An epochal opportunity to elucidate the pathogenic mechanisms of psychiatric disorders has
emerged from advances in genomic technology, new computational tools and the growth of …
emerged from advances in genomic technology, new computational tools and the growth of …
Education, smoking, and cohort change: Forwarding a multidimensional theory of the environmental moderation of genetic effects
Sociologists interested in the effects of genes on complex social outcomes claim
environmental conditions structure when and how genes matter, but they have only studied …
environmental conditions structure when and how genes matter, but they have only studied …
Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA
Heroin, nicotine, cocaine, and MDMA are abused by billions of people. They are believed to
target midbrain dopamine neurons and/or serotonin neurons, but their effects on the …
target midbrain dopamine neurons and/or serotonin neurons, but their effects on the …
Genome-wide association study of familial lung cancer
J Byun, AG Schwartz, C Lusk, AS Wenzlaff… - …, 2018 - academic.oup.com
To identify genetic variation associated with lung cancer risk, we performed a genome-wide
association analysis of 685 lung cancer cases that had a family history of two or more first or …
association analysis of 685 lung cancer cases that had a family history of two or more first or …
Propofol suppresses growth, migration and invasion of A549 cells by down-regulation of miR-372
H Sun, D Gao - BMc cancer, 2018 - Springer
Background Propofol, a commonly used intravenous anesthetic during cancer resection
surgery, has been found to exhibit tumor inhibitory effects in vitro and in vivo. The role of …
surgery, has been found to exhibit tumor inhibitory effects in vitro and in vivo. The role of …
Germline mutations in young non-smoking women with lung adenocarcinoma
I Donner, R Katainen, LJ Sipilä, M Aavikko, E Pukkala… - Lung Cancer, 2018 - Elsevier
Objectives Although the primary cause of lung cancer is smoking, a considerable proportion
of all lung cancers occur in never smokers. Gender influences the risk and characteristics of …
of all lung cancers occur in never smokers. Gender influences the risk and characteristics of …