Nicotine is a highly addictive drug found in tobacco that drives its continued use despite the
harmful consequences. The initiation of nicotine abuse involves the mesolimbic dopamine …

Lung cancer is the most common cancer worldwide and has high rates of mortality. The
major risk factor associated with this disease is tobacco smoke, but approximately 10 …

Lung cancer is the leading cause of cancer death worldwide. Cigarette smoking is the most
common risk factor for lung carcinoma; other risks include genetic factors and exposure to …

Nicotinic acetylcholine receptors (nAChRs) are major signalling molecules in the central and
peripheral nervous system. Over the last decade, they have been linked to a number of …

Theranostics cover emerging technologies for cell biomarking for disease diagnosis and
targeted introduction of drug ingredients to specific malignant sites. Theranostics …

Neurotensin receptor-3 or sortilin is a vacuolar protein sorting 10 protein domain (Vps10p)
has been firstly discovered in the human brain, it acts as receptor or co-receptor of the cell …

Recent studies have showed that α5 nicotinic acetylcholine receptor (α5‐nAChR) is closely
associated with nicotine‐related lung cancer. Our previous studies also demonstrated that …

Nicotinic acetylcholine receptors (nAChRs) are pentameric ligand-gated ion channels
responsible for rapid neural and neuromuscular signal transmission. Although it is well …

Over the last decade, robust human genetic findings have been instrumental in elucidating
the heritable basis of nicotine addiction (NA). They highlight coding and synonymous …

The roles of α5‐nicotinic acetylcholine receptors (α5‐nAChRs) in various types of solid
cancer have been reported; however, its role in melanoma remains unknown. We knocked …