[HTML][HTML] Lipolysis: cellular mechanisms for lipid mobilization from fat stores

GF Grabner, H Xie, M Schweiger, R Zechner - Nature metabolism, 2021 - nature.com
The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

[HTML][HTML] Cholesterol-rich lipid rafts as platforms for SARS-CoV-2 entry

SN Palacios-Rapalo, LA De Jesus-Gonzalez… - Frontiers in …, 2021 - frontiersin.org
Since its appearance, the Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV-2),
the causal agent of Coronavirus Disease 2019 (COVID-19), represents a global problem for …

[HTML][HTML] A genome-wide CRISPR screen identifies host factors that regulate SARS-CoV-2 entry

Y Zhu, F Feng, G Hu, Y Wang, Y Yu, Y Zhu… - Nature …, 2021 - nature.com
The global spread of SARS-CoV-2 is posing major public health challenges. One feature of
SARS-CoV-2 spike protein is the insertion of multi-basic residues at the S1/S2 subunit …

Dissecting lipid metabolism alterations in SARS-CoV-2

I Casari, M Manfredi, P Metharom, M Falasca - Progress in lipid research, 2021 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the cause of the COVID-
19 pandemic that has infected over a hundred million people globally. There have been …

Cholesterol, lipoproteins, and COVID-19: Basic concepts and clinical applications

E Kočar, T Režen, D Rozman - … et Biophysica Acta (BBA)-Molecular and …, 2021 - Elsevier
Cholesterol is being recognized as a molecule involved in regulating the entry of the SARS-
CoV-2 virus into the host cell. However, the data about the possible role of cholesterol …

[HTML][HTML] Coronavirus infection and cholesterol metabolism

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …

[HTML][HTML] Cepharanthine: A review of the antiviral potential of a Japanese-approved alopecia drug in COVID-19

M Rogosnitzky, P Okediji, I Koman - Pharmacological Reports, 2020 - Springer
Cepharanthine (CEP) is a naturally occurring alkaloid derived from Stephania cepharantha
Hayata and demonstrated to have unique anti-inflammatory, antioxidative …

[HTML][HTML] The roles of lipids in SARS-CoV-2 viral replication and the host immune response

KN Theken, SY Tang, S Sengupta, GA FitzGerald - Journal of lipid research, 2021 - ASBMB
The significant morbidity and mortality associated with severe acute respiratory syndrome
coronavirus 2 infection has underscored the need for novel antiviral strategies. Lipids play …

[HTML][HTML] Role of endolysosomes in severe acute respiratory syndrome coronavirus-2 infection and coronavirus disease 2019 pathogenesis: implications for potential …

N Khan, X Chen, JD Geiger - Frontiers in pharmacology, 2020 - frontiersin.org
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is an enveloped, single-
stranded RNA virus. Humans infected with SARS-CoV-2 develop a disease known as …

SARS-CoV-2 neuronal invasion and complications: potential mechanisms and therapeutic approaches

O Swain, SK Romano, R Miryala, J Tsai… - Journal of …, 2021 - Soc Neuroscience
Clinical reports suggest that the coronavirus disease-19 (COVID-19) pandemic caused by
severe acute respiratory syndrome (SARS)-coronavirus-2 (CoV-2) has not only taken …