Sex, as well as meiotic recombination between homologous chromosomes, is nearly
ubiquitous among eukaryotes. In those species that use it, recombination is important for …

While recombination is widely recognized to be a key modulator of numerous evolutionary
phenomena, we have a poor understanding of how recombination rate itself varies and …

Meiosis is a specialized cell division that gives rise to genetically distinct gametic cells.
Meiosis relies on the tightly controlled formation of DNA double-strand breaks (DSBs) and …

Meiotic chromosomes have a loop/axis architecture, with axis length determining crossover
frequency. Meiosis-specific Pds5 depletion mutants have shorter chromosome axes and …

The genomic landscape of recombination plays an essential role in evolution. Patterns of
recombination are highly variable along chromosomes, between sexes, individuals …

Meiosis is the foundation of sexual reproduction, and crossover recombination is one
hallmark of meiosis. Crossovers establish the physical connections between homolog …

Failure of homologous chromosomes to recombine is arguably the most important cause of
human meiotic nondisjunction, having been linked to numerous autosomal and sex …

In most species that reproduce sexually, successful gametogenesis requires recombination
during meiosis. The number and placement of crossovers (COs) vary among individuals …

Meiotic recombination is an essential biological process that ensures proper chromosome
segregation and creates genetic diversity. Individual variation in global recombination rates …

Using single-cell whole-genome sequencing to identify crossover locations along
chromosomes in a large number of human sperm cells, Bell et al. 1 find that, in cells and …