Histamine is a transmitter in the nervous system and a signaling molecule in the gut, the
skin, and the immune system. Histaminergic neurons in mammalian brain are located …

Dorsal root ganglion (DRG) sensory neuron subtypes defined by their in vivo properties
display distinct intrinsic electrical properties. We used bulk RNA sequencing of genetically …

Histaminergic neurons in the tuberomammillary nucleus (TMN) are an important component
of the ascending arousal system and may form part of a “flip–flop switch” hypothesized to …

Histaminergic (HA) neurons, found in the posterior hypothalamic tuberomammillary nucleus
(TMN), extend fibers throughout the brain and exert modulatory influence over numerous …

Painful diabetic neuropathy (PDN) is a common complication of diabetes mellitus and
adversely affects the patients' quality of life. Evidence has accumulated that PDN is …

Highlights•The therapeutic principle of K v 1.5 inhibition for AF treatment is not understood.•I
Kur/K v 1.5 inhibition can result in action potential shortening in atrial cardiomyocytes.•Poor …

The action potential (AP) is a fundamental feature of excitable cells that serves as the basis
for long-distance signaling in the nervous system. There is considerable diversity in the …

Globus pallidus (GP) neurons fire rhythmically in the absence of synaptic input, suggesting
that they may encode their inputs as changes in the phase of their rhythmic firing. Action …

We analyzed ionic currents that regulate pacemaking in dopaminergic neurons of the mouse
ventral tegmental area by comparing voltage trajectories during spontaneous firing with …

The dorsal root ganglion (DRG) contains heterogeneous populations of sensory neurons
including primary nociceptive neurons and C-fibers implicated in pain signaling. Recent …