Therapeutic targets and interventional strategies in COVID-19: mechanisms and clinical studies

YW Zhou, Y Xie, LS Tang, D Pu, YJ Zhu… - Signal transduction and …, 2021 - nature.com
Owing to the limitations of the present efforts on drug discovery against severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) and the lack of the understanding of the …

SARS-CoV-2 antiviral therapy

K Tao, PL Tzou, J Nouhin, H Bonilla… - Clinical microbiology …, 2021 - Am Soc Microbiol
The development of effective antiviral therapy for COVID-19 is critical for those awaiting
vaccination, as well as for those who do not respond robustly to vaccination. This review …

Current prevention of COVID-19: natural products and herbal medicine

J Huang, G Tao, J Liu, J Cai, Z Huang… - Frontiers in …, 2020 - frontiersin.org
Starting from December 2019, novel coronavirus disease 2019 (COVID-19) pandemic has
caused tremendous economic loss and unprecedented health crisis across the globe. While …

On facing the SARS-CoV-2 (COVID-19) with combination of nanomaterials and medicine: possible strategies and first challenges

VS Sivasankarapillai, AM Pillai, A Rahdar, AP Sobha… - Nanomaterials, 2020 - mdpi.com
Global health is facing the most dangerous situation regarding the novel severe acute
respiratory syndrome called coronavirus 2 (SARS-CoV-2), which is widely known as the …

Repurposing existing drugs for the treatment of COVID-19/SARS-CoV-2 infection: A review describing drug mechanisms of action

H Yousefi, L Mashouri, SC Okpechi, N Alahari… - Biochemical …, 2021 - Elsevier
The outbreak of a novel coronavirus (SARS-CoV-2) has caused a major public health
concern across the globe. SARS-CoV-2 is the seventh coronavirus that is known to cause …

Drug combinations as a first line of defense against coronaviruses and other emerging viruses

JM White, JT Schiffer, RA Bender Ignacio, S Xu… - MBio, 2021 - Am Soc Microbiol
The world was unprepared for coronavirus disease 2019 (COVID-19) and remains ill-
equipped for future pandemics. While unprecedented strides have been made developing …

Inhalation delivery for the treatment and prevention of COVID-19 infection

BB Eedara, W Alabsi, D Encinas-Basurto, R Polt… - Pharmaceutics, 2021 - mdpi.com
Coronavirus disease-2019 (COVID-19) is caused by coronavirus-2 (SARS-CoV-2) and has
produced a global pandemic. As of 22 June 2021, 178 million people have been affected …

Strategies to target SARS-CoV-2 entry and infection using dual mechanisms of inhibition by acidification inhibitors

C Prabhakara, R Godbole, P Sil, S Jahnavi… - PLoS …, 2021 - journals.plos.org
Many viruses utilize the host endo-lysosomal network for infection. Tracing the endocytic
itinerary of SARS-CoV-2 can provide insights into viral trafficking and aid in designing new …

COVID-19 detection in chest X-ray images using a new channel boosted CNN

SH Khan, A Sohail, A Khan, YS Lee - Diagnostics, 2022 - mdpi.com
COVID-19 is a respiratory illness that has affected a large population worldwide and
continues to have devastating consequences. It is imperative to detect COVID-19 at the …

Molecular mechanisms and epidemiology of COVID-19 from an allergist's perspective

K Hosoki, A Chakraborty, S Sur - Journal of Allergy and Clinical …, 2020 - Elsevier
The global pandemic caused by the newly described severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) has caused worldwide suffering and death of unimaginable …