Objective To determine the benefits and harms of medical cannabis and cannabinoids for
chronic pain. Design Systematic review and meta-analysis. Data sources MEDLINE …

Musculoskeletal pain is a challenging condition for both patients and physicians. Many
adults have experienced one or more episodes of musculoskeletal pain at some time of their …

Importance Harms and benefits of opioids for chronic noncancer pain remain unclear.
Objective To systematically review randomized clinical trials (RCTs) of opioids for chronic …

Abstract The Visual Analogue Scale (VAS), Numeric Rating Scale (NRS), and Pain Severity
subscale of the Brief Pain Inventory (BPI-PS) are the most frequently used instruments to …

Background Chronic pain is defined as pain lasting beyond normal tissue healing time,
generally taken to be 12 weeks. It contributes to disability, anxiety, depression, sleep …

This review examines evidence for the effectiveness of cannabinoids in chronic noncancer
pain (CNCP) and addresses gaps in the literature by: considering differences in outcomes …

Abstract The recently proposed Analgesic, Anesthetic, and Addiction Clinical Trial
Translations, Innovations, Opportunities, and Networks (ACTTION)-American Pain Society …

Clinical question What is the role of medical cannabis or cannabinoids for people living with
chronic pain due to cancer or non-cancer causes? Current practice Chronic pain is common …

Background Over the past 2 decades, the use of intravenous ketamine infusions as a
treatment for chronic pain has increased dramatically, with wide variation in patient …

Manual therapy interventions are popular among individual health care providers and their
patients; however, systematic reviews do not strongly support their effectiveness. Small …