E3 ubiquitin ligase-mediated regulation of bone formation and tumorigenesis
N Severe, FX Dieudonne, PJ Marie - Cell death & disease, 2013 - nature.com
The ubiquitination–proteasome and degradation system is an essential process that
regulates protein homeostasis. This system is involved in the regulation of cell proliferation …
regulates protein homeostasis. This system is involved in the regulation of cell proliferation …
Phospho-specific Smad3 signaling: impact on breast oncogenesis
E Tarasewicz, JS Jeruss - Cell Cycle, 2012 - Taylor & Francis
Members of the TGFβ superfamily are known to exert a myriad of physiologic and pathologic
growth controlling influences on mammary development and oncogenesis. In epithelial …
growth controlling influences on mammary development and oncogenesis. In epithelial …
miR-124-3p functions as a tumor suppressor in breast cancer by targeting CBL
Y Wang, L Chen, Z Wu, M Wang, F Jin, N Wang, X Hu… - BMC cancer, 2016 - Springer
Background The origin and development of breast cancer remain complex and obscure.
Recently, microRNA (miRNA) has been identified as an important regulator of the initiation …
Recently, microRNA (miRNA) has been identified as an important regulator of the initiation …
Genome-wide microRNA expression profiling in idiopathic non-obstructive azoospermia: significant up-regulation of miR-141, miR-429 and miR-7-1-3p
STUDY QUESTION What is the profile of miRNAs in seminal plasma of patients with non-
obstructive azoospermia (NOA)? SUMMARY ANSWER miR-141, miR-429 and miR-7-1-3p …
obstructive azoospermia (NOA)? SUMMARY ANSWER miR-141, miR-429 and miR-7-1-3p …
[PDF][PDF] c-Cbl-mediated neddylation antagonizes ubiquitination and degradation of the TGF-β type II receptor
Transforming growth factor β (TGF-β) is a potent antiproliferative factor in multiple types of
cells. Deregulation of TGF-β signaling is associated with the development of many cancers …
cells. Deregulation of TGF-β signaling is associated with the development of many cancers …
KIAA1324 suppresses gastric cancer progression by inhibiting the oncoprotein GRP78
Recent advances in genome and transcriptome analysis have contributed to the
identification of many potential cancer-related genes. Furthermore, biological and clinical …
identification of many potential cancer-related genes. Furthermore, biological and clinical …
Randomized trial of weight loss in primary breast cancer: Impact on body composition, circulating biomarkers and tumor characteristics
W Demark‐Wahnefried, LQ Rogers… - … journal of cancer, 2020 - Wiley Online Library
Obesity adversely impacts overall and cancer‐specific survival among breast cancer
patients. Preclinical studies demonstrate negative energy balance inhibits cancer …
patients. Preclinical studies demonstrate negative energy balance inhibits cancer …
Cytoplasmic DRAK1 overexpressed in head and neck cancers inhibits TGF-β1 tumor suppressor activity by binding to Smad3 to interrupt its complex formation with …
Head and neck squamous cell carcinoma (HNSCC) is an extremely aggressive cancer with
a poor prognosis and low patient survival. Because chemotherapy for advanced HNSCC is …
a poor prognosis and low patient survival. Because chemotherapy for advanced HNSCC is …
Potential diagnostic and prognostic utility of miR-141, miR-181b1, and miR-23b in breast cancer
miRNAs, a group of short noncoding RNAs, are key regulators of fundamental cellular
processes and signaling pathways. Dysregulation of miRNA expression with known …
processes and signaling pathways. Dysregulation of miRNA expression with known …
Classification models for Invasive Ductal Carcinoma Progression, based on gene expression data-trained supervised machine learning
Early detection of breast cancer and its correct stage determination are important for
prognosis and rendering appropriate personalized clinical treatment to breast cancer …
prognosis and rendering appropriate personalized clinical treatment to breast cancer …