[HTML][HTML] Biology of Acinetobacter baumannii: Pathogenesis, Antibiotic Resistance Mechanisms, and Prospective Treatment Options

CR Lee, JH Lee, M Park, KS Park, IK Bae… - Frontiers in cellular …, 2017 - frontiersin.org
Acinetobacter baumannii is undoubtedly one of the most successful pathogens responsible
for hospital-acquired nosocomial infections in the modern healthcare system. Due to the …

Platforms for antibiotic discovery

K Lewis - Nature reviews Drug discovery, 2013 - nature.com
The spread of resistant bacteria, leading to untreatable infections, is a major public health
threat but the pace of antibiotic discovery to combat these pathogens has slowed down …

[HTML][HTML] Antimicrobial resistance in Acinetobacter baumannii: From bench to bedside

MF Lin, CY Lan - World Journal of Clinical Cases: WJCC, 2014 - ncbi.nlm.nih.gov
Acinetobacter baumannii (A. baumannii) is undoubtedly one of the most successful
pathogens in the modern healthcare system. With invasive procedures, antibiotic use and …

Acinetobacter baumannii: Emergence of a Successful Pathogen

AY Peleg, H Seifert, DL Paterson - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Acinetobacter baumannii has emerged as a highly troublesome pathogen for many
institutions globally. As a consequence of its immense ability to acquire or upregulate …

Global evolution of multidrug-resistant Acinetobacter baumannii clonal lineages

R Zarrilli, S Pournaras, M Giannouli… - International journal of …, 2013 - Elsevier
The rapid expansion of Acinetobacter baumannii clinical isolates exhibiting resistance to
carbapenems and most or all available antibiotics during the last decade is a worrying …

Metallo-β-lactamases: a last frontier for β-lactams?

G Cornaglia, H Giamarellou… - The Lancet infectious …, 2011 - thelancet.com
Metallo-β-lactamases are resistance determinants of increasing clinical relevance in Gram-
negative bacteria. Because of their broad range, potent carbapenemase activity and …

鲍曼不动杆菌抗生素多重耐药性: 耐药机制与感染治疗对策

凌保东 - 中国抗生素杂志, 2010 - cqvip.com
多重以及泛耐药鲍曼不动杆菌导致的感染流行已成为全球关注的公共卫生问题.
大多数细菌耐药基因与表型特征均充分反映在耐药鲍曼不动杆菌. 鲍曼不动杆菌的外膜通透屏障 …

[HTML][HTML] Carbapenemases: Transforming Acinetobacter baumannii into a Yet More Dangerous Menace

MS Ramirez, RA Bonomo, ME Tolmasky - Biomolecules, 2020 - mdpi.com
Acinetobacter baumannii is a common cause of serious nosocomial infections. Although
community-acquired infections are observed, the vast majority occur in people with …

Global Challenge of Multidrug-Resistant Acinetobacter baumannii

F Perez, AM Hujer, KM Hujer, BK Decker… - Antimicrobial agents …, 2007 - Am Soc Microbiol
We may soon be facing the end of the “antibiotic era.” The initial and seemingly unstoppable
success of antibiotics, the fruit of human ingenuity, has been countered by an escalation of …

The Epidemiology and Control of Acinetobacter baumannii in Health Care Facilities

PE Fournier, H Richet… - Clinical infectious …, 2006 - academic.oup.com
Acinetobacter baumannii is a ubiquitous pathogen capable of causing both community and
health care—associated infections (HAIs), although HAIs are the most common form. This …