Emerging broad-spectrum resistance in Pseudomonas aeruginosa and Acinetobacter baumannii: mechanisms and epidemiology

A Potron, L Poirel, P Nordmann - International journal of antimicrobial …, 2015 - Elsevier
Multidrug resistance is quite common among non-fermenting Gram-negative rods, in
particular among clinically relevant species including Pseudomonas aeruginosa and …

Acinetobacter baumannii: Emergence of a Successful Pathogen

AY Peleg, H Seifert, DL Paterson - Clinical microbiology reviews, 2008 - Am Soc Microbiol
Acinetobacter baumannii has emerged as a highly troublesome pathogen for many
institutions globally. As a consequence of its immense ability to acquire or upregulate …

Extended-spectrum β-lactamases: a clinical update

DL Paterson, RA Bonomo - Clinical microbiology reviews, 2005 - Am Soc Microbiol
Extended-spectrum β-lactamases (ESBLs) are a rapidly evolving group of β-lactamases
which share the ability to hydrolyze third-generation cephalosporins and aztreonam yet are …

Global Challenge of Multidrug-Resistant Acinetobacter baumannii

F Perez, AM Hujer, KM Hujer, BK Decker… - Antimicrobial agents …, 2007 - Am Soc Microbiol
We may soon be facing the end of the “antibiotic era.” The initial and seemingly unstoppable
success of antibiotics, the fruit of human ingenuity, has been countered by an escalation of …

The new β-lactamases

GA Jacoby, LS Munoz-Price - New England Journal of Medicine, 2005 - Mass Medical Soc
The β-lactamases are the major bacterial defense of gram-negative bacteria against β-
lactam antibiotics. This review details the many types of β-lactamases, explains how they …

Mechanisms of Multidrug Resistance in Acinetobacter Species and Pseudomonas aeruginosa

RA Bonomo, D Szabo - Clinical infectious diseases, 2006 - academic.oup.com
Acinetobacter species and Pseudomonas aeruginosa are noted for their intrinsic resistance
to antibiotics and for their ability to acquire genes encoding resistance determinants …

Multidrug-resistant Acinetobacter baumannii: mechanisms of virulence and resistance

NC Gordon, DW Wareham - International journal of antimicrobial agents, 2010 - Elsevier
Infection due to Acinetobacter baumannii has become a significant challenge to modern
healthcare systems. The organism shows a formidable capacity to develop antimicrobial …

Resistance to β-lactam antibiotics

K Poole - Cellular and Molecular Life Sciences CMLS, 2004 - Springer
Abstract β-lactams have a long history in the treatment of infectious diseases, though their
use has been and continues to be confounded by the development of resistance in target …

[HTML][HTML] Capacity of multidrug-resistant clinical isolates of Acinetobacter baumannii to form biofilm and adhere to epithelial cell surfaces

HW Lee, YM Koh, J Kim, JC Lee, YC Lee… - Clinical microbiology …, 2008 - Elsevier
This study evaluated the capacity of 23 multidrug-resistant (MDR) clinical isolates of
Acinetobacter baumannii to adhere to respiratory epithelial cell surfaces and to form biofilm …

Acinetobacter baumannii: a universal threat to public health?

H Giamarellou, A Antoniadou… - International journal of …, 2008 - Elsevier
Acinetobacter spp. are non-fermentative, strictly aerobic, Gram-negative microorganisms
with a confusing taxonomic history. The Acinetobacter baumannii–Acinetobacter …