Precision medicine for obesity: current evidence and insights for personalization of obesity pharmacotherapy
Obesity is a chronic and complex disease associated with increased morbidity, mortality,
and financial burden. It is expected that by 2030 one of two people in the United States will …
and financial burden. It is expected that by 2030 one of two people in the United States will …
Type-2 diabetes mellitus remission prediction models after Roux-En-Y gastric bypass and sleeve gastrectomy based on disease severity scores
Aim Metabolic and bariatric surgery (MBS) is considered one of the most effective
interventions for weight loss and associated type-2 diabetes mellitus (T2DM) remission …
interventions for weight loss and associated type-2 diabetes mellitus (T2DM) remission …
Type 2 Diabetes Remission in Patients with Heterozygous Variants in the Leptin-Melanocortin Pathway after Roux-en-Y Gastric Bypass: A Matched Case–Control …
Background Roux-en-Y gastric bypass (RYGB) is associated with a high rate of type 2
diabetes (T2D) remission. Carriers of heterozygous variants in the leptin-melanocortin …
diabetes (T2D) remission. Carriers of heterozygous variants in the leptin-melanocortin …
Leptin‐Melanocortin pathway variants and gastric emptying in patients with obesity
Background Accelerated gastric emptying (GE) is a trait seen in obesity. Mutations in the
hypothalamic leptin‐melanocortin 4 receptor (Leptin‐MC4R) pathway have been associated …
hypothalamic leptin‐melanocortin 4 receptor (Leptin‐MC4R) pathway have been associated …
The association between microvascular and macrovascular diseases and diabetes remission after bariatric surgery
Background Type-2 diabetes mellitus (T2DM) results in detrimental vascular complications
including both microvascular and macrovascular diseases. Roux-en-Y gastric bypass …
including both microvascular and macrovascular diseases. Roux-en-Y gastric bypass …