Key Points Discusses issues affecting the definition of oral cancer and makes the case that
emerging differences in the aetiology of the disease at different sites requires oral cavity …

Oral squamous cell carcinoma (OSCC) is the most common type of oral cancer worldwide
and in the United States. OSCC remains a major cause of morbidity and mortality in patients …

Alcohol drinking is an established risk factor for several malignancies, and it is a potentially
modifiable risk factor for cancer. The Cancer Prevention Committee of the American Society …

Importance Case-control studies show a possible relationship between oral bacteria and
head and neck squamous cell cancer (HNSCC). Prospective studies are needed to examine …

Tobacco smoking and alcohol consumption are well‐established risk factors for head and
neck cancer. The prognostic role of smoking and alcohol intake at diagnosis have been less …

Background Oropharyngeal squamous cell carcinomas (OPSCCs) are traditionally caused
by smoking and excessive alcohol consumption. However, in the last decades high-risk …

Background Tobacco and alcohol consumption are known causes of cancer. We set out to
estimate the absolute numbers and proportions of cancer attributable to smoking and high …

Despite the development of standard therapies, including surgery, radiotherapy and
chemotherapy, survival rates for head and neck squamous cell carcinoma (HNSCC) have …

Abstract Problem/Condition: Tobacco use is the leading preventable cause of cancer,
contributing to at least 12 types of cancer, including acute myeloid leukemia (AML) and …

Importance Second primary malignant neoplasms (SPMNs) are the leading cause of death
in survivors of head and neck squamous cell carcinoma (HNSCC). Recently, human …