Head and neck squamous cell carcinoma

DE Johnson, B Burtness, CR Leemans… - Nature reviews Disease …, 2020 - nature.com
Most head and neck cancers are derived from the mucosal epithelium in the oral cavity,
pharynx and larynx and are known collectively as head and neck squamous cell carcinoma …

A review of the 8th edition of the AJCC staging system for oropharyngeal cancer according to HPV status

P Machczyński, E Majchrzak, P Niewinski… - European Archives of …, 2020 - Springer
Background The incidence of oropharyngeal squamous cell carcinoma (OPSCC) has
increased substantially in recent decades, particularly p16-positive human papillomavirus …

National, regional, and global burdens of disease from 2000 to 2016 attributable to alcohol use: a comparative risk assessment study

K Shield, J Manthey, M Rylett, C Probst… - The Lancet Public …, 2020 - thelancet.com
Background Alcohol use has increased globally, with varying trends in different parts of the
world. This study investigates gender, age, and geographical differences in the alcohol …

Global trends in oral and pharyngeal cancer incidence and mortality

C Bosetti, G Carioli, C Santucci… - … journal of cancer, 2020 - Wiley Online Library
To provide an up‐to‐date overview of recent trends in mortality from oral and pharyngeal
cancer, we analyzed death certification data for 61 countries worldwide provided by the …

A multivariable Mendelian randomization analysis investigating smoking and alcohol consumption in oral and oropharyngeal cancer

M Gormley, T Dudding, E Sanderson, RM Martin… - Nature …, 2020 - nature.com
The independent effects of smoking and alcohol in head and neck cancer are not clear,
given the strong association between these risk factors. Their apparent synergistic effect …

A defucosylated anti‑CD44 monoclonal antibody 5‑mG2a‑f exerts antitumor effects in mouse xenograft models of oral squamous cell carcinoma

J Takei, MK Kaneko, T Ohishi… - Oncology …, 2020 - spandidos-publications.com
CD44 is widely expressed on the surface of most tissues and all hematopoietic cells, and
regulates many genes associated with cell adhesion, migration, proliferation, differentiation …

Tobacco, alcohol and family history of cancer as risk factors of Oral Squamous Cell Carcinoma: Case-control retrospective study

G Tenore, A Nuvoli, A Mohsen, A Cassoni, A Battisti… - Applied Sciences, 2020 - mdpi.com
The aim of the study is to observe retrospectively the correlation between Oral Squamous
Cell Carcinoma (OSCC) and risk factors; including tobacco, alcohol and Family History of …

Oral cavity and lip cancer in the world: an epidemiological review

H Salehiniya, M Raei - Biomedical Research and Therapy, 2020 - eprints.bmsu.ac.ir
Background: One of the most common cancers is squamous cell carcinoma of the head and
neck which is a serious health challenge worldwide. Considering the importance of …

[HTML][HTML] Incidence and mortality of laryngeal cancer in China, 2015

Y He, D Liang, D Li, B Shan, R Zheng… - Chinese Journal of …, 2020 - ncbi.nlm.nih.gov
Objective Using data from cancer registries to estimate laryngeal cancer incidence and
mortality in China, 2015. Methods Data submitted from 501 cancer registries were checked …

Extracapsular extension of neck nodes and absence of human papillomavirus 16‐DNA are predictors of impaired survival in p16‐positive oropharyngeal squamous …

J Freitag, T Wald, T Kuhnt, T Gradistanac, M Kolb… - Cancer, 2020 - Wiley Online Library
Background Human papillomavirus (HPV)‐driven oropharyngeal squamous cell carcinomas
(OPSCCs) demonstrate superior outcome compared with HPV‐negative OPSCCs. The …