STAT3 and its targeting inhibitors in oral squamous cell carcinoma

M Jiang, B Li - Cells, 2022 - mdpi.com
Oral squamous cell carcinoma (OSCC) usually originates from the precancerous lesions of
oral mucosa and accounts for approximately 90% of oral cancers. Current therapeutic …

[HTML][HTML] Reviewing the epidemiology of head and neck cancer: definitions, trends and risk factors

M Gormley, G Creaney, A Schache, K Ingarfield… - British Dental …, 2022 - nature.com
Introduction Head and neck cancer appears to be increasing in incidence, with potential
changes in aetiology proposed. This paper aims to provide a narrative overview of the …

[HTML][HTML] HPV and head and neck cancers: Towards early diagnosis and prevention

L Galati, S Chiocca, D Duca, M Tagliabue… - Tumour Virus …, 2022 - Elsevier
Head and neck squamous cell carcinoma (HNSCC) is the sixth most common cancer
worldwide with an increasing trend of its incidence. Alcohol consumption, smoking, and viral …

[HTML][HTML] Human papillomavirus-associated head and neck cancers. Where are we now? A systematic review

M Pinkiewicz, K Dorobisz, T Zatoński - Cancer Management and …, 2022 - ncbi.nlm.nih.gov
Background Human papillomavirus targets the skin and mucous membranes, producing
benign hyperplastic lesions and precancerous and cancerous lesions. An increasing …

Alcohol and head and neck cancer: updates on the role of oxidative stress, genetic, epigenetics, oral microbiota, antioxidants, and alkylating agents

G Ferraguti, S Terracina, C Petrella, A Greco, A Minni… - Antioxidants, 2022 - mdpi.com
Head and neck cancer (HNC) concerns more than 890,000 patients worldwide annually and
is associated with the advanced stage at presentation and heavy outcomes. Alcohol …

The world of Oral cancer and its risk factors viewed from the aspect of MicroRNA expression patterns

O Aghiorghiesei, O Zanoaga, A Nutu, C Braicu… - Genes, 2022 - mdpi.com
Oral cancer is one of the leading causes of death worldwide, with a reported 5-year survival
rate of around 50% after treatment. Epigenetic modifications are considered to have a key …

The evolving epidemiology of oral cavity and oropharyngeal cancers

AK Chaturvedi, ND Freedman, CC Abnet - Cancer Research, 2022 - AACR
In 1988, Blot and colleagues reported results from a US case–control study of oral cavity or
pharyngeal (oropharyngeal and hypopharyngeal) cancers, with results showing …

Evaluation of optimal threshold of neutrophil-lymphocyte ratio and its association with survival outcomes among patients with head and neck cancer

SJ Ma, H Yu, M Khan, J Gill, S Santhosh… - JAMA Network …, 2022 - jamanetwork.com
Importance Given the role of inflammation in cancer progression, neutrophil-lymphocyte
ratio (NLR) from peripheral blood has been suggested as a readout of systemic …

Precision medicine in head and neck cancers: genomic and preclinical approaches

G Miserocchi, C Spadazzi, S Calpona… - Journal of Personalized …, 2022 - mdpi.com
Head and neck cancers (HNCs) represent the sixth most widespread malignancy worldwide.
Surgery, radiotherapy, chemotherapeutic and immunotherapeutic drugs represent the main …

[HTML][HTML] Immunotherapy in head and neck squamous cell carcinoma: An updated review

K Parmar, A Mohamed, E Vaish, R Thawani… - Cancer Treatment and …, 2022 - Elsevier
Squamous cell cancer of the head and neck (HNSCC) is the sixth most common cancer and
is associated with significant morbidity and mortality. The tumor microenvironment for …