Cigarette smoke-induced respiratory response: insights into cellular processes and biomarkers

SR Cha, J Jang, SM Park, SM Ryu, SJ Cho, SR Yang - Antioxidants, 2023 - mdpi.com
Cigarette smoke (CS) poses a significant risk factor for respiratory, vascular, and organ
diseases owing to its high content of harmful chemicals and reactive oxygen species (ROS) …

RNA-based liquid biopsy in head and neck cancer

J Kabzinski, A Kucharska-Lusina, I Majsterek - Cells, 2023 - mdpi.com
Head and neck cancer (HNC) is a prevalent and diverse group of malignancies with
substantial morbidity and mortality rates. Early detection and monitoring of HNC are crucial …

CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma

F Hoffmann, A Franzen, L de Vos, L Wuest, Z Kulcsár… - Clinical …, 2023 - Springer
Background The majority of patients with recurrent or metastasized head and neck
squamous cell carcinoma (HNSCC) do not benefit from immune checkpoint blockade (ICB) …

Modifiable risk factors for oral cavity cancer in non-smokers: A systematic review and meta-analysis

MA Heller, SC Nyirjesy, R Balsiger, N Talbot… - Oral Oncology, 2023 - Elsevier
Background Oral cavity cancer (OCC) is traditionally associated with smoking, but there is
an increasing prevalence of the disease among non-smokers. This review investigates …

Evaluating the effect of metabolic traits on oral and oropharyngeal cancer risk using Mendelian randomization

M Gormley, T Dudding, SJ Thomas, J Tyrrell, AR Ness… - Elife, 2023 - elifesciences.org
Abstract A recent World Health Organization report states that at least 40% of all cancer
cases may be preventable, with smoking, alcohol consumption, and obesity identified as …

CYP4F12 is a potential biomarker and inhibits cell migration of head and neck squamous cell carcinoma via EMT pathway

W Jia, S Chen, R Wei, X Yang, M Zhang, Y Qian… - Scientific Reports, 2023 - nature.com
Head and neck squamous cell carcinoma (HNSC) is the most common malignant tumor of
head and neck. Due to the insidious nature of HNSC and the lack of effective early …

Combination therapy with oncolytic viruses and immune checkpoint inhibitors in head and neck squamous cell carcinomas: an approach of complementary …

H Dong, M Li, C Yang, W Wei, X He, G Cheng… - Cancer Cell …, 2023 - Springer
Squamous cell carcinomas are the most common head and neck malignancies. Significant
progress has been made in standard therapeutic methods combining surgery, radiation, and …

[HTML][HTML] Inhibiting the inhibitors: Development of the IAP inhibitor xevinapant for the treatment of locally advanced squamous cell carcinoma of the head and neck

RL Ferris, K Harrington, JD Schoenfeld… - Cancer Treatment …, 2023 - Elsevier
Standard of care for patients with locally advanced squamous cell carcinoma of the head
and neck (LA SCCHN) is surgery followed by chemoradiotherapy (CRT) or definitive CRT …

A new detection method of oral and oropharyngeal squamous cell carcinoma based on multivariate analysis of surface enhanced raman spectra of salivary exosomes

CI Faur, C Dinu, V Toma, A Jurj, R Mărginean… - Journal of Personalized …, 2023 - mdpi.com
Raman spectroscopy recently proved a tremendous capacity to identify disease-specific
markers in various (bio) samples being a non-invasive, rapid, and reliable method for cancer …

Risk factors for head and neck cancer in more and less developed countries: Analysis from the INHANCE consortium

N Goyal, M Hennessy, E Lehman, W Lin… - Oral …, 2023 - Wiley Online Library
Objective We analyzed the pooled case‐control data from the International Head and Neck
Cancer Epidemiology (INHANCE) consortium to compare cigarette smoking and alcohol …