Adverse childhood experiences and the consequences on neurobiological, psychosocial, and somatic conditions across the lifespan
JI Herzog, C Schmahl - Frontiers in psychiatry, 2018 - frontiersin.org
Introduction: Adverse childhood experiences (ACE) such as sexual and physical abuse or
neglect are frequent in childhood and constitute a massive stressor with long-lasting …
neglect are frequent in childhood and constitute a massive stressor with long-lasting …
Annual research review: enduring neurobiological effects of childhood abuse and neglect
MH Teicher, JA Samson - Journal of child psychology and …, 2016 - Wiley Online Library
Background Childhood maltreatment is the most important preventable cause of
psychopathology accounting for about 45% of the population attributable risk for childhood …
psychopathology accounting for about 45% of the population attributable risk for childhood …
The effects of chronic stress on the human brain: From neurotoxicity, to vulnerability, to opportunity
For the last five decades, science has managed to delineate the mechanisms by which
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …
stress hormones can impact on the human brain. Receptors for glucocorticoids are found in …
Post-traumatic stress disorder
Post-traumatic stress disorder (PTSD) occurs in 5–10% of the population and is twice as
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
common in women as in men. Although trauma exposure is the precipitating event for PTSD …
Childhood maltreatment and psychopathology: A case for ecophenotypic variants as clinically and neurobiologically distinct subtypes
MH Teicher, JA Samson - American journal of psychiatry, 2013 - Am Psychiatric Assoc
Objective Childhood maltreatment increases risk for psychopathology. For some highly
prevalent disorders (major depression, substance abuse, anxiety disorders, and …
prevalent disorders (major depression, substance abuse, anxiety disorders, and …
The effects of poverty on childhood brain development: the mediating effect of caregiving and stressful life events
Importance The study provides novel data to inform the mechanisms by which poverty
negatively impacts childhood brain development. Objective To investigate whether the …
negatively impacts childhood brain development. Objective To investigate whether the …
A quantitative meta-analysis of neurocognitive functioning in posttraumatic stress disorder.
Posttraumatic stress disorder (PTSD) is associated with regional alterations in brain
structure and function that are hypothesized to contribute to symptoms and cognitive deficits …
structure and function that are hypothesized to contribute to symptoms and cognitive deficits …
Adverse childhood experiences, allostasis, allostatic load, and age-related disease
A Danese, BS McEwen - Physiology & behavior, 2012 - Elsevier
How do adverse childhood experiences get 'under the skin'and influence health outcomes
through the life-course? Research reviewed here suggests that adverse childhood …
through the life-course? Research reviewed here suggests that adverse childhood …
Sex differences in anxiety disorders: interactions between fear, stress, and gonadal hormones
This article is part of a Special Issue “SBN 2014”. Women are more vulnerable to stress-and
fear-based disorders, such as anxiety and post-traumatic stress disorder. Despite the …
fear-based disorders, such as anxiety and post-traumatic stress disorder. Despite the …
Post-traumatic stress disorder: the neurobiological impact of psychological trauma
JE Sherin, CB Nemeroff - Dialogues in clinical neuroscience, 2011 - Taylor & Francis
The classic fight-or-flight response to perceived threat is a reflexive nervous phenomenon
thai has obvious survival advantages in evolutionary terms. However, the systems that …
thai has obvious survival advantages in evolutionary terms. However, the systems that …