Insulin-like growth factor I (IGF-I) is a polypeptide hormone produced mainly by the liver in
response to the endocrine GH stimulus, but it is also secreted by multiple tissues for …

Insulin resistance as a hallmark of type 2 DM (T2DM) plays a role in dementia by promoting
pathological lesions or enhancing the vulnerability of the brain. Numerous studies related to …

Resveratrol possesses beneficial biological effects, which include anti-oxidant, anti-
inflammatory and anti-carcinogenic properties. Recently, resveratrol has been shown to …

Chronic cerebral hypoperfusion (CCH) is a common pathophysiological state that usually
occurs in conditions such as vascular dementia and Alzheimer's disease, both of which are …

Parkinson's disease (PD) is a neurodegenerative disorder that results in the death of
dopaminergic neurons within the substantia nigra pars compacta and the reduction in …

It is well-established that reperfusion following cerebral ischemic injury gives rise to
secondary injury accompanied by structural and functional damage. However, it remains …

Currently, there is no effective therapy for chronic cerebral hypoperfusion-induced
subcortical ischemic vascular dementia (SIVD), which displays cognitive deficits and …

Objective To assess the association of insulin-like growth factor 1 (IGF-1) with the risk of
incident ischaemic stroke and outcome after ischaemic stroke. Design A systematic review of …

Dementia is a major cause of disability and dependency among older people. If the lives of
people with dementia are to be improved, research and its translation into druggable target …

Vascular cognitive impairment (VCI) is the second most common cause of cognitive deficit
after Alzheimer's disease. Since VCI patients represent an important target population for …