Crohn's disease

G Roda, S Chien Ng, PG Kotze, M Argollo… - Nature Reviews …, 2020 - nature.com
Crohn's disease is an inflammatory bowel disease that is characterized by chronic
inflammation of any part of the gastrointestinal tract, has a progressive and destructive …

Management of Crohn disease: a review

K Cushing, PDR Higgins - Jama, 2021 - jamanetwork.com
Importance Crohn disease, a chronic gastrointestinal inflammatory disease, is increasing in
incidence and prevalence in many parts of the world. Uncontrolled inflammation leads to …

ACG clinical guideline: management of Crohn's disease in adults

GR Lichtenstein, EV Loftus, KL Isaacs… - Official journal of the …, 2018 - journals.lww.com
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

ECCO guidelines on therapeutics in Crohn's disease: medical treatment

J Torres, S Bonovas, G Doherty… - Journal of Crohn's …, 2020 - academic.oup.com
2. Methods Based on the GRADE workflow, the Guidelines Committee of ECCO [GuiCom]
selected a panel of 48 experts supported by a team of methodologists and librarians …

Effect of tight control management on Crohn's disease (CALM): a multicentre, randomised, controlled phase 3 trial

JF Colombel, R Panaccione, P Bossuyt, M Lukas… - The Lancet, 2017 - thelancet.com
Background Biomarkers of intestinal inflammation, such as faecal calprotectin and C-
reactive protein, have been recommended for monitoring patients with Crohn's disease, but …

Approach to the management of recently diagnosed inflammatory bowel disease patients: a user's guide for adult and pediatric gastroenterologists

M Agrawal, EA Spencer, JF Colombel, RC Ungaro - Gastroenterology, 2021 - Elsevier
Inflammatory bowel diseases (IBDs), including Crohn's disease and ulcerative colitis, are
chronic, progressive, immune-mediated diseases of adults and children that have no cure …

ECCO guidelines on therapeutics in Crohn's disease: surgical treatment

M Adamina, S Bonovas, T Raine… - Journal of Crohn's …, 2020 - academic.oup.com
This article is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the management of Crohn's …

Mechanisms, management, and treatment of fibrosis in patients with inflammatory bowel diseases

F Rieder, C Fiocchi, G Rogler - Gastroenterology, 2017 - Elsevier
In the last 10 years, we have learned much about the pathogenesis, diagnosis, and
management of intestinal fibrosis in patients with inflammatory bowel diseases. Just a …

Location is important: differentiation between ileal and colonic Crohn's disease

R Atreya, B Siegmund - Nature Reviews Gastroenterology & …, 2021 - nature.com
Crohn's disease can affect any part of the gastrointestinal tract; however, current European
and national guidelines worldwide do not differentiate between small-intestinal and colonic …

Crohn's disease

J Torres, S Mehandru, JF Colombel, L Peyrin-Biroulet - The Lancet, 2017 - thelancet.com
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with
increasing incidence worldwide. Crohn's disease might result from a complex interplay …