British Society of Gastroenterology consensus guidelines on the management of inflammatory bowel disease in adults

CA Lamb, NA Kennedy, T Raine, PA Hendy, PJ Smith… - Gut, 2019 - gut.bmj.com
Ulcerative colitis and Crohn's disease are the principal forms of inflammatory bowel disease.
Both represent chronic inflammation of the gastrointestinal tract, which displays …

Efficacy of biological therapies and small molecules in moderate to severe ulcerative colitis: systematic review and network meta-analysis

NE Burr, DJ Gracie, CJ Black, AC Ford - Gut, 2022 - gut.bmj.com
Objective Biological therapies and small molecules continue to be evaluated in moderate to
severely active ulcerative colitis, but are often studied in placebo-controlled trials, meaning …

ACG clinical guideline: management of Crohn's disease in adults

GR Lichtenstein, EV Loftus, KL Isaacs… - Official journal of the …, 2018 - journals.lww.com
Crohn's disease is an idiopathic inflammatory disorder of unknown etiology with genetic,
immunologic, and environmental influences. The incidence of Crohn's disease has steadily …

[PDF][PDF] Third European evidence-based consensus on diagnosis and management of ulcerative colitis. Part 2: current management

M Harbord, R Eliakim, D Bettenworth… - Journal of Crohn's …, 2017 - academic.oup.com
11.1. General The treatment strategy for ulcerative colitis [UC] is mainly based on the
severity, distribution [proctitis, left-sided, extensive] 1 and pattern of disease. The latter …

A comprehensive review and update on Crohn's disease

M Gajendran, P Loganathan, AP Catinella… - Disease-a-month, 2018 - Elsevier
The term inflammatory bowel disease (IBD) refers principally to two major categories of
chronic relapsing inflammatory intestinal disorders: Crohn's disease (CD) and ulcerative …

Natural history of adult ulcerative colitis in population-based cohorts: a systematic review

M Fumery, S Singh, PS Dulai… - Clinical …, 2018 - Elsevier
Background & Aims A comprehensive knowledge of the natural history of ulcerative colitis
(UC) helps understand disease evolution, identify poor prognostic markers and impact of …

[HTML][HTML] Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study

I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig… - The Lancet, 2016 - thelancet.com
Background Crohn's disease and ulcerative colitis are the two major forms of inflammatory
bowel disease; treatment strategies have historically been determined by this binary …

Combination therapy with infliximab and azathioprine is superior to monotherapy with either agent in ulcerative colitis

R Panaccione, S Ghosh, S Middleton, JR Márquez… - Gastroenterology, 2014 - Elsevier
Background & Aims The comparative efficacy and safety of infliximab and azathioprine
therapy alone or in combination for ulcerative colitis (UC) have not been evaluated …

[HTML][HTML] Revisiting inflammatory bowel disease: pathology, treatments, challenges and emerging therapeutics including drug leads from natural products

K Yeshi, R Ruscher, L Hunter, NL Daly… - Journal of clinical …, 2020 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic and life-long disease characterized by
gastrointestinal tract inflammation. It is caused by the interplay of the host's genetic …

Crohn's disease

J Torres, S Mehandru, JF Colombel, L Peyrin-Biroulet - The Lancet, 2017 - thelancet.com
Crohn's disease is a chronic inflammatory disease of the gastrointestinal tract, with
increasing incidence worldwide. Crohn's disease might result from a complex interplay …