Lung cancer is the most common cause of cancer death worldwide, with over one million
cases annually. To identify genetic factors that modify disease risk, we conducted a genome …

To identify risk variants for lung cancer, we conducted a multistage genome-wide
association study. In the discovery phase, we analyzed 315,450 tagging SNPs in 1,154 …

Smoking is a leading cause of preventable death, causing about 5 million premature deaths
worldwide each year,. Evidence for genetic influence on smoking behaviour and nicotine …

Common variants in the nicotinic acetylcholine receptor gene cluster on chromosome 15q24-
25.1 were associated with lung cancer risk in three recently published independently …

Smoking is a common risk factor for many diseases. We conducted genome-wide
association meta-analyses for the number of cigarettes smoked per day (CPD) in smokers …

Lung cancer is the leading cause of cancer death worldwide, and cigarette smoking is the
major environmental factor for its development. To elucidate the genetic differences in the …

Nicotine dependence risk and lung cancer risk are associated with variants in a region of
chromosome 15 encompassing genes encoding the nicotinic receptor subunits CHRNA5 …

To identify common genetic variants that contribute to lung cancer susceptibility, we
conducted a multistage genome-wide association study of lung cancer in Asian women who …

Abstract A locus at 15q24/15q25. 1, which includes the nicotinic acetylcholine receptor A
subunits 3 and 5 (CHRNA3 and CHRNA5) genes, has recently been associated with lung …

To find additional susceptibility loci for lung cancer, we tested promising associations from
our previous genome-wide association study (GWAS) of lung cancer in the Chinese …