CHRONIC TOXICITY TEST OF 4-ETHOXY-2-METHYL-5-MORPHOLINO-3 (2H)-PYRIDAZINONE (M73101) IN BEAGLE DOGS
C ONODERA, T HAYASHI, I MAKITA… - The Journal of …, 1979 - jstage.jst.go.jp
Abstracts------Male and female beagle dogs, aged 17–21 months, were ad-ministered orally
M 73101 (0, 60, 120 and 240 mg/kg/day), a new analgesic and antiinflammatory drug, for 27
weeks, and following recovery test was carried out for 5 weeks. lDead animals were not
found throughout the experimental period. Body weight gain, and food and water
consumption were not affected due to M 73101 administration. Except for a slight increase of
vomitting in the highest dose, there were no abnormal symptoms. Biochemical examination …
M 73101 (0, 60, 120 and 240 mg/kg/day), a new analgesic and antiinflammatory drug, for 27
weeks, and following recovery test was carried out for 5 weeks. lDead animals were not
found throughout the experimental period. Body weight gain, and food and water
consumption were not affected due to M 73101 administration. Except for a slight increase of
vomitting in the highest dose, there were no abnormal symptoms. Biochemical examination …
CHRONIC TOXICITY TEST OF 4-ETHOXY-2-METHYL-5-MORPHOLINO-3 (2H)-PYRIDAZINONE (M73101) IN BEAGLE DOGS
小野寺千秋， 林俊文， 牧田市郎， 橋高志… - The Journal of …, 1979 - jlc.jst.go.jp
Male and female beagle dogs, aged 17-21 months, were administered orally M 73101 (0,
60, 120 and 240 mg/kg/day), a new analgesic and antiinflammatory drug, for 27 weeks, and
following recovery test was carried out for 5 weeks. Dead animals were not found throughout
the experimental period. Body weight gain, and food and water consumption were not
affected due to M73101 administration. Except for a slight increase of vomitting in the
highest dose, there were no abnormal symptoms. Biochemical examination showed the …
60, 120 and 240 mg/kg/day), a new analgesic and antiinflammatory drug, for 27 weeks, and
following recovery test was carried out for 5 weeks. Dead animals were not found throughout
the experimental period. Body weight gain, and food and water consumption were not
affected due to M73101 administration. Except for a slight increase of vomitting in the
highest dose, there were no abnormal symptoms. Biochemical examination showed the …