5′, 6′-Dehydroguiachrysine and 5′, 6′-dehydroguiaflavine, two curarizing quaternary indole alkaloids from the stem bark of Strychnos guianensis
J Penelle, P Christen, J Molgó, M Tits, V Brandt… - Phytochemistry, 2001 - Elsevier
Two new quaternary indole alkaloids 5′, 6′-dehydroguiachrysine (1) and 5′, 6′-
dehydroguiaflavine (2) were isolated from Strychnos guianensis stem bark. Their structures
were determined by analysis of spectral data. Their inhibitory effects on neuromuscular
transmission are also reported and compared to that of other quaternary alkaloids.
dehydroguiaflavine (2) were isolated from Strychnos guianensis stem bark. Their structures
were determined by analysis of spectral data. Their inhibitory effects on neuromuscular
transmission are also reported and compared to that of other quaternary alkaloids.
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