A test procedure for the determination of (2-methoxyethoxy) acetic acid in urine from jet fuel-exposed mice

C B'hymer, DE Keil, KL Cheever - Toxicology Mechanisms and …, 2005 - Taylor & Francis
A test procedure for the determination of (2-methoxyethoxy) acetic acid (MEAA) was adapted
and applied to urine samples from jet fuel (JP-8)-exposed mice using capillary gas
chromatography with a mass selective detector (MSD). MEAA is a metabolite and proposed
biomarker for exposure to 2-(2-methoxyethoxy) ethanol, a glycol ether component in the
formulation of JP-8. The collected urine samples were spiked with deuterated butoxyacetic
acid internal standard, and extracted with ethyl acetate, and esterified with ethanol and …
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