A comprehensive immunohistochemistry of prostaglandins F2α and E2 synthetic enzymes in rat ovary and uterus around parturition

H Satoh, K Watanabe, M Kawaminami… - Prostaglandins & Other …, 2013 - Elsevier
A comprehensive immunohistochemistry with the isoform-distinguishable antibodies against
prostaglandin (PG) F 2α and PGE 2 biosynthetic enzymes was undertaken to identify the
cellular types and enzyme isoforms in rat ovary and uterus around parturition. In general
ovarian and uterine cells showed positive immunoreactions for phospholipase A 2 groups
4A and 6A, but not group 2A, and cyclooxygenase (COX)-1 rather than COX-2. Their
immunoreactions for PGF 2α synthase and PGE 2 synthase were cell type-dependently …
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