J. Neurochem.(2008) 104, 1565–1576. Abstract Chondroitin sulfate (CS) is a major
microenvironmental molecule in the CNS, and there have been few reports about its
neuroprotective activity. As neuronal cell death by excitotoxicity is a crucial phase in many
neuronal diseases, we examined the effect of various CS preparations on neuronal cell
death induced by the excitotoxicity of glutamate analogs. CS preparations were added to
cultured neurons before and after the administration of glutamate analogs. Then, the extents …

… A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino acid-induced
neuronal cell death 高硫酸化コンドロイチン硫酸,CS-Eは,興奮性アミノ酸による神経細胞死を抑制
する … A highly sulfated chondroitin sulfate preparation, CS-E, prevents excitatory amino
acid-induced neuronal cell death … 高硫酸化コンドロイチン硫酸,CS-Eは,興奮性アミノ酸による
神経細胞死を抑制する …