A new furan derivative from an endophytic Aspergillus tubingensis of Decaisnea insignis (Griff.) Hook.f. & Thomson
X Yang, N Wang, Y Kang, Y Ma - Natural product research, 2019 - Taylor & Francis
X Yang, N Wang, Y Kang, Y Ma
Natural product research, 2019•Taylor & FrancisA new furan derivative named 3-(5-oxo-2, 5-dihydrofuran-3-yl) propanoic acid (1) was
isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the
single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and
antibacterial activities of compound 1 was tested, it exhibited potent antifungal activity
against Fusarium graminearum with MIC value of 16 µg/mL and medium antibacterial
activity against Streptococcus lactis with MIC value of 32 µg/mL.
isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the
single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and
antibacterial activities of compound 1 was tested, it exhibited potent antifungal activity
against Fusarium graminearum with MIC value of 16 µg/mL and medium antibacterial
activity against Streptococcus lactis with MIC value of 32 µg/mL.
Abstract
A new furan derivative named 3-(5-oxo-2,5-dihydrofuran-3-yl) propanoic acid (1) was isolated for the first time. Its structure was elucidated by UV, IR, NMR, HR-ESI-MS and the single-crystal X-ray diffraction spectroscopic data. Meanwhile, the antifungal and antibacterial activities of compound 1 was tested, it exhibited potent antifungal activity against Fusarium graminearum with MIC value of 16 µg/mL and medium antibacterial activity against Streptococcus lactis with MIC value of 32 µg/mL.
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